HPV相关性口咽鳞状细胞癌中p16免疫组化局部阳性的预后意义
发布时间：2018-12-19 21:39
【摘要】：正肿瘤抑制蛋白p16免疫组化染色是评价人乳头状瘤病毒(HPV)感染状态的主要依据,同时p16阳性也是提示HPV相关性口咽鳞状细胞癌预后良好的标志物。目前p16阳性重要的评价指标包括p16阳性细胞数及阳性融合细胞数,通常将75%阳性细胞定义为p16阳性,而≤25%阳性细胞定义为p16阴性,另外将50%阳性细胞且伴25%融
[Abstract]:Immunohistochemical staining of positive tumor suppressor protein p16 is the main basis for evaluating the status of (HPV) infection of human papillomavirus (HPV), and the positive expression of p16 is also a good prognostic marker for HPV associated oropharyngeal squamous cell carcinoma (OSCC). At present, the number of p16 positive cells and the number of positive fusion cells are the most important indexes for p16 positive, which usually define 75% of positive cells as p16 positive, 鈮，
本文编号：2387503
[Abstract]:Immunohistochemical staining of positive tumor suppressor protein p16 is the main basis for evaluating the status of (HPV) infection of human papillomavirus (HPV), and the positive expression of p16 is also a good prognostic marker for HPV associated oropharyngeal squamous cell carcinoma (OSCC). At present, the number of p16 positive cells and the number of positive fusion cells are the most important indexes for p16 positive, which usually define 75% of positive cells as p16 positive, 鈮，
本文编号：2387503
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