咽喉反流在任克间隙水肿发病中的作用

发布时间：2018-12-25 13:17

【摘要】：目的:探讨咽喉反流在任克间隙水肿发病中的作用。方法:选取2014-02-2016-06诊断为任克间隙水肿的16例患者进行分析,以同期声带白斑和早期声门型喉癌50例患者作为对照组,对比分析两组间反流症状指数(RSI)、反流体征评分(RFS)、24h咽喉酸反流次数、24h咽喉酸反流时间和咽喉反流阳性率的差异。结果:任克间隙水肿患者的RSI评分均值为11.2±3.8,RFS评分均值为8.2±1.5,中位反流次数4.0[0.0;9.0]次,中位反流时间5.6[0.0;16.7]min,量表评分咽喉反流阳性率100%(16/16),24hMII-pH监测结果示咽喉反流阳性率56.2%(9/16);对照组RSI评分均值为8.6±3.2,RFS评分均值为6.8±2.1,中位反流次数0.0[0.0;3.0]次,中位反流时间0.0[0.0;4.3]min,量表评分咽喉反流阳性率58.0%(29/50),24hMII-pH监测结果示咽喉反流阳性率28.0%(14/50)。任克间隙水肿组RSI评分、RFS评分、24h咽喉酸反流次数、24h咽喉酸反流时间和咽喉反流阳性率均显著高于对照组,差异有统计学意义(P0.01或P0.05)。结论:咽喉反流与任克间隙水肿具有相关性,咽喉反流在任克间隙水肿发病中起一定作用,对任克间隙水肿患者治疗时应加抑酸治疗。
[Abstract]:Objective: to investigate the role of throat reflux in the pathogenesis of interstitial edema in Renke. Methods: sixteen patients diagnosed as Renke space edema from 2014-02-2016-06 were analyzed. 50 patients with vocal cord leukoplakia and early glottic laryngeal carcinoma were selected as control group. The index of reflux symptom index (RSI),) between the two groups was compared and analyzed. The difference of (RFS), 24 h laryngeal acid reflux times, 24 h laryngeal acid reflux time and throat reflux positive rate was observed. Results: the mean value of RSI score was 11.2 卤3.8m, the median number of reflux was 4.0 [0.09] and the median time of reflux was 5.6 [0.090]. 16.7 the positive rate of throat reflux in min, scale was 100% (16 / 16). The positive rate of throat reflux was 56.2% (9 / 16) by 24hMII-pH. In the control group, the mean RSI score was 8.6 卤3.2, the mean score was 6.8 卤2.1, the median number of reflux was 0.0 [0.03.0], and the median reflux time was 0.0 [0.030]. 4.3] the positive rate of throat reflux was 58.0% (29 / 50) in min, scale and 28.0% (14 / 50) in 24hMII-pH. The RSI score, RFS score, 24 h throat acid reflux times, 24 h laryngeal acid reflux time and the positive rate of throat reflux were significantly higher in Renke interstitial edema group than those in the control group (P0.01 or P0.05). Conclusion: there is a correlation between throat reflux and Renke interstitial edema. Throat reflux plays a certain role in the pathogenesis of Renke interstitial edema. Acid suppression should be added in the treatment of Renke interstitial edema.
【作者单位】：海军总医院耳鼻咽喉头颈外科;
【基金】：海军总医院创新培育基金(No:CXPY201624)
【分类号】：R767.4

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