丙酸氟替卡松气雾剂联合盐酸西替利嗪滴剂治疗儿童哮喘合并变应性鼻炎

发布时间：2019-02-20 21:41

【摘要】：目的观察丙酸氟替卡松气雾剂联合盐酸西替利嗪滴剂治疗儿童哮喘合并变应性鼻炎的临床疗效。方法将120例患儿(4~12岁)随机分为观察组和对照组,每组各60例。观察组使用丙酸氟替卡松气雾剂联合盐酸西替利嗪滴剂治疗,对照组单纯使用丙酸氟替卡松气雾剂,疗程均为12周。治疗结束后,评价临床疗效。结果两组哮喘均达到完全控制,且第1秒用力呼气容积(FEV1)治疗后比治疗前明显提高(P0.05)。观察组过敏性鼻炎的喷嚏、流涕、鼻堵、鼻痒等症状明显好转,视觉模拟评分总有效率达96.7%,对照组为81.7%,观察组明显优于对照组(P0.01),无明显不良反应。结论丙酸氟替卡松气雾剂联合盐酸西替利嗪滴剂在治疗儿童哮喘合并变应性鼻炎的临床疗效及肺功能变化等方面疗效优于单独使用丙酸氟替卡松气雾剂。
[Abstract]:Objective to observe the clinical effect of fluticasone propionate aerosol combined with cetirizine hydrochloride in the treatment of asthmatic children with allergic rhinitis. Methods 120 children (4 ~ 12 years old) were randomly divided into observation group (n = 60) and control group (n = 60). The observation group was treated with fluticasone propionate aerosol combined with cetirizine hydrochloride drops, while the control group was treated with fluticasone propionate aerosol for 12 weeks. After the treatment, the clinical effect was evaluated. Results the asthma of both groups reached complete control and the forced expiratory volume (FEV1) after 1 second treatment was significantly higher than that before treatment (P0.05). The symptoms of allergic rhinitis, such as sneezing, runny nose, nasal obstruction and itching, were obviously improved in the observation group. The total effective rate of visual analogue score was 96.7 in the observation group and 81.7 in the control group. The observation group was obviously superior to the control group (P0.01), and there was no obvious adverse reaction. Conclusion fluticasone propionate aerosol combined with cetirizine hydrochloride is superior to fluticasone propionate aerosol in the treatment of asthmatic children with allergic rhinitis.
【作者单位】：上海市普陀区人民医院儿科;
【分类号】：R725.6;R765.21

【相似文献】