声带息肉患者持续元音及连贯言语声的倒频谱声学分析

发布时间：2019-03-09 13:01

【摘要】：目的探讨倒频谱声学分析法与连贯言语声学信号用于鉴别病理性声信号的价值。方法分别采集26例成人声带息肉患者(息肉组,男10例,女16例)及27例正常嗓音者(正常组,男13例,女14例)持续元音和连贯言语声信号,采用MDVP(multi dimensional voice program)软件分析各组持续元音频率微扰(jitter)和振幅微扰(shimmer),采用ADSV(analysis of dysphonia in speech and voice)软件分析各组持续元音和连贯言语的倒频谱参数:倒频谱峰值突出(cepstral peak prominence,CPP)、低高频谱能量比(the mean ratio of singnal energy below 4000Hz to the energy above 4 000Hz,L/HSR)、CPP的标准差(STD CPP)、L/HSR的标准差(STD L/HSR)及发音障碍倒频谱指数(the cepstral/spectral index of dysphonia,CSID),分析扰动参数和倒频谱参数对鉴别病理声学信号的敏感性。结果正常组持续元音的jitter和shimmer值均小于声带息肉组(P0.05);除STD L/HSR外,正常组持续元音的倒频谱参数值均高于息肉组(P0.05);连贯言语的倒频谱参数中,男性声带息肉组的CPP、L/HSR均低于男性正常组(P0.05),女性声带息肉组CPP值明显低于女性正常组(P0.05)。男女性持续元音声信号的倒频谱参数CPP和CSID在ROC曲线下的面积与参考值0.5相比,差异有统计学意义(P0.05);男性连贯言语声的CPP及L/HSR、女性CPP ROC曲线下的面积与参考值0.5的差异有统计学意义(P0.05)。结论连贯言语声和持续元音的扰动参数和倒频谱参数均可用于区别正常与声带息肉患者的噪音声学信号,倒频谱参数CPP对区别正常和声带息肉患者嗓音信号有较好的特异度和灵敏度。
[Abstract]:Objective to explore the value of cepstrum acoustic analysis and coherent speech acoustic signals in the identification of pathological acoustic signals. Methods persistent vowels and coherent speech signals were collected in 26 adult patients with polyp of vocal cord (polyp group, 10 males, 16 females) and 27 normal speakers (normal group, 13 males and 14 females). Analysis of continuous vowel frequency perturbed (jitter) and amplitude perturbed (shimmer), in each group by MDVP (multi dimensional voice program) software The cepstrum parameters of continuous vowel and coherent speech in each group were analyzed by ADSV (analysis of dysphonia in speech and voice) software: cepstrum peak prominent (cepstral peak prominence,CPP, low spectral energy ratio (the mean ratio of singnal energy below 4000Hz to the energy above 4000Hz, L/HSR). The standard deviation (STD L/HSR) of (STD CPP), L/HSR and the cepstrum index (the cepstral/spectral index of dysphonia,CSID) of CPP were used to analyze the sensitivity of disturbance parameters and cepstrum parameters to differential diagnosis of pathological acoustic signals. Results the jitter and shimmer values of the continuous vowels in the normal group were lower than those in the vocal cord polyp group (P0.05), except for STD L/HSR, the Cepstrum parameters of the continuous vowels in the normal group were higher than those in the polyp group (P0.05). The CPP,L/HSR of male vocal cord polyp group was lower than that of male normal group (P0.05), and the CPP value of female vocal cord polyp group was significantly lower than that of female normal group (P0.05). The Cepstral parameters (CPP and CSID) of male and female persistent vowels were significantly different from the reference value (P0.05) under the ROC curve. There was a significant difference between the area under the CPP ROC curve and the reference value of CPP and L-HSR in male coherent speech sounds (P0.05). Conclusion the perturbed parameters and cepstrum parameters of continuous vowels and continuous vowels can be used to distinguish the noise acoustic signals between normal and vocal cord polyp patients. The cepstrum parameter CPP has good specificity and sensitivity in distinguishing vocal signal between normal and vocal cord polyps.
【作者单位】：厦门大学附属中山医院耳鼻咽喉科;厦门大学;
【基金】：国家自然科学基金(NSFC81371080) 福建省卫生系统中青年骨干人才培养项目(2013-ZQN-JC-35)联合资助
【分类号】：R767.92

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