多层螺旋CT对于OSAHS成人患者上气道阻塞平面定位的Meta分析

发布时间：2019-04-22 16:23

【摘要】：目的：多导睡眠监测技术一直是诊断阻塞性睡眠呼吸暂停低通气综合征的金标准，但其无法对上气道阻塞点进行准确定位。近年来有众多关于多层螺旋CT评价OSAHS成人患者上气道阻塞平面的研究。本次Meta分析在于系统评价多层螺旋CT对于OSAHS成人患者上气道阻塞平面进行准确定位的临床诊断价值。方法：在Pubmed、Medline、Cochran图书馆及中国数字化期刊网/万方数据库检索检索国内外1990～2012年发表，有关多层螺旋CT在阻塞性睡眠呼吸暂停低通气综合征中的应用价值的文献，，数据采用随机效应模型进行统计。结果：共纳入7篇参考文献，即多层螺旋CT对于OSAHS成人患者上气道阻塞平面的应用研究,其灵敏度和特异度分别为90%（95%CI86%～93%）、91%（95%CI87%～95%）。SROC曲线下面积0.9594。结论：多层螺旋CT可以较好的定位OSAHS成人患者上气道的阻塞平面，可以作为重要辅助检查方法之一，用于指导临床诊断和治疗。
[Abstract]:Aim: polysomnography has always been the golden standard for the diagnosis of obstructive sleep apnea hypopnea syndrome (OSAS), but it can not accurately locate the obstructive point of upper airway in patients with obstructive sleep apnea hypopnea syndrome (OSAS). In recent years, there have been many studies on the evaluation of upper airway obstruction in adult patients with OSAHS by multi-slice spiral CT. The purpose of this Meta analysis is to evaluate the diagnostic value of multi-slice spiral CT in the diagnosis of upper airway obstruction in adult patients with OSAHS. Methods: the domestic and foreign literatures published from 1990 to 2012 were searched in Pubmed,Medline,Cochran Library and China Digital Journal Network / Wanfang Database. The literature about the application value of multi-slice spiral CT in obstructive sleep apnea hypopnea syndrome (OSAS) was reviewed. The data were analyzed by random effect model. Results: a total of 7 references were included. The sensitivity and specificity of multi-slice spiral CT for upper airway occlusion in adult patients with OSAHS were 90% (95% CI 86%, 93%), respectively. 91% (95% CI 87% / 95%). The area under the SROC curve is 0.959 4. Conclusion: multi-slice spiral CT can better locate the obstruction plane of upper airway in adult patients with OSAHS. It can be used as one of the important auxiliary examination methods to guide clinical diagnosis and treatment.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R766

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