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50岁以上中心性浆液性脉络膜视网膜病变患者的脉络膜厚度分析

发布时间:2019-05-17 13:55
【摘要】:目的观察50岁以上中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSC)患者的脉络膜厚度水平。方法选择2016年1月至2017年1月在我院确诊为CSC的50岁以上患者25例纳入研究。其中单眼20例,双眼5例,分为CSC患眼组(30眼),CSC对侧健眼组(19眼)。选择同期年龄匹配的健康人26例(26眼)作为正常对照组。使用光学相干断层扫描加强深度成像技术进行脉络膜厚度的测量,选取中心凹下,距离中心凹鼻侧500μm、1500μm,颞侧500μm、1500μm共5个位点。结果 CSC患者年龄为(60.08±7.68)岁。CSC患眼组、CSC对侧健眼组中心凹下脉络膜厚度(subfoveal choroidal thickness,SFCT)分别为(414.17±85.88)μm、(352.89±97.22)μm,较正常对照组的(280.69±90.99)明显增厚(均为P0.05)。单眼CSC患者患眼SFCT为(414.17±85.88)μm,较CSC对侧健眼的(352.89±97.22)μm明显增厚(P=0.008)。其余测量位点组间差异结果相似。结论 50岁以上CSC患者脉络膜较年龄匹配正常人明显增厚,患眼SFCT多在400μm以上,这一特征有助于对老龄合并黄斑神经上皮脱离患者的鉴别诊断。
[Abstract]:Objective to observe the level of choroid thickness in patients over 50 years old with central serous chorioretinopathy (central serous chorioretinopathy,CSC). Methods from January 2016 to January 2017, 25 patients over 50 years old with CSC diagnosed in our hospital were enrolled in the study. Among them, 20 cases were monocular and 5 cases were binocular. They were divided into CSC eye group (30 eyes) and), CSC contralateral healthy eye group (19 eyes). 26 healthy people (26 eyes) with age matching in the same period were selected as the normal control group. The choroid thickness was measured by optical coherence tomography enhanced depth imaging. Five sites below the central fovea, 500 渭 m, 1500 渭 m from the nose side, 500 渭 m and 1500 渭 m from the temporal side were selected. Results the age of patients with CSC was (60.008 卤7.68) years old. The thickness of choroid under fovea in CSC group and contralateral group were (414.17 卤85.88) 渭 m and (352.89 卤97. 22) 渭 m, respectively. Compared with the normal control group (280.69 卤90. 99), it was significantly thicker than that of the normal control group (P 0.05). The SFCT of monocular CSC patients was (414.17 卤85.88) 渭 m, which was significantly thicker than that of the contralateral healthy eyes of CSC (352.89 卤9722) 渭 m (P 鈮,

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