白内障术前应用聚维酮碘冲洗结膜囊效果的系统评价
发布时间：2019-06-06 15:09
【摘要】：目的：白内障术前常规应用冲洗液冲洗结膜囊预防眼内炎的发生。如何正确评估与选择合适的结膜囊冲洗液,是一个值得探讨的问题。本文分析了白内障术前应用聚维酮碘、生理盐水及抗生素冲洗结膜囊的临床对照试验,讨论聚维酮碘较其他冲洗液冲洗结膜囊是否能有效降低结膜囊细菌阳性率,预防眼内炎症发生。 方法：检索Medline、Pubmed、Ovid、The Cochrane Library、EMBASE及中国生物医学文献数据库发表的有关聚维酮碘、生理盐水及抗生素在白内障术前冲洗结膜囊效果的对照研究,并辅以手工检索、因特网搜索。共纳入4篇文章6项试验,分为两组对其疗效进行分析。 结果：聚维酮碘冲洗组与生理盐水冲洗组相比能显著降低结膜囊细菌阳性率,差异有显著性(P0.0001),合并RR值为0.15,95%CI为[0.05,0.45],与抗生素冲洗组比较有显著差别,差异有显著性(P0.05),合并RR值为0.38,95%CI为[0.17,0.83]。 结论：白内障术前应用聚维酮碘冲洗结膜囊较生理盐水及抗生素冲洗能显著降低术后结膜囊细菌培养阳性率,预防眼内炎症的发生。
[Abstract]:Objective: to prevent the occurrence of endophthalmitis by washing conjunctival capsule with washing solution before cataract surgery. How to correctly evaluate and select the appropriate conjunctival capsule flushing solution is a problem worthy of discussion. This paper analyzes the clinical controlled trial of washing conjunctival capsule with povidone iodine, saline and antibiotics before cataract surgery, and discusses whether povidone iodine can effectively reduce the bacterial positive rate of conjunctival capsule compared with other flushing solution. Prevent the occurrence of inflammation in the eye. Methods: a comparative study of povidone iodine, saline and antibiotics published by Medline,Pubmed,Ovid,The Cochrane Library,EMBASE and Chinese Biomedical Literature Database on the effect of washing conjunctival capsule before cataract surgery was searched, supplemented by manual retrieval. Internet search. A total of 4 articles and 6 trials were included and divided into two groups to analyze the curative effect. Results: compared with saline washing group, povidone iodine washing group significantly decreased the positive rate of conjunctival capsule bacteria (P0.0001). The RR value of povidone iodine washing group was 0.15, 95% CI was 0.05, 0.45). Compared with antibiotic flushing group, there was significant difference (P 0.05). The combined RR value was 0.38 and 95% CI was 0.17, 0.83 respectively. Conclusion: compared with saline and antibiotic flushing, washing conjunctival capsule with povidone iodine before cataract surgery can significantly reduce the positive rate of bacterial culture in conjunctival capsule and prevent the occurrence of intraocular inflammation.
【学位授予单位】：南京大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R779.66
本文编号：2494394
[Abstract]:Objective: to prevent the occurrence of endophthalmitis by washing conjunctival capsule with washing solution before cataract surgery. How to correctly evaluate and select the appropriate conjunctival capsule flushing solution is a problem worthy of discussion. This paper analyzes the clinical controlled trial of washing conjunctival capsule with povidone iodine, saline and antibiotics before cataract surgery, and discusses whether povidone iodine can effectively reduce the bacterial positive rate of conjunctival capsule compared with other flushing solution. Prevent the occurrence of inflammation in the eye. Methods: a comparative study of povidone iodine, saline and antibiotics published by Medline,Pubmed,Ovid,The Cochrane Library,EMBASE and Chinese Biomedical Literature Database on the effect of washing conjunctival capsule before cataract surgery was searched, supplemented by manual retrieval. Internet search. A total of 4 articles and 6 trials were included and divided into two groups to analyze the curative effect. Results: compared with saline washing group, povidone iodine washing group significantly decreased the positive rate of conjunctival capsule bacteria (P0.0001). The RR value of povidone iodine washing group was 0.15, 95% CI was 0.05, 0.45). Compared with antibiotic flushing group, there was significant difference (P 0.05). The combined RR value was 0.38 and 95% CI was 0.17, 0.83 respectively. Conclusion: compared with saline and antibiotic flushing, washing conjunctival capsule with povidone iodine before cataract surgery can significantly reduce the positive rate of bacterial culture in conjunctival capsule and prevent the occurrence of intraocular inflammation.
【学位授予单位】：南京大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R779.66
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相关期刊论文 前4条
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