在药物治疗基础上的心理干预对持续性中—重度变应性鼻炎的疗效分析

发布时间：2019-06-26 17:35

【摘要】：目的观察在药物治疗基础上的心理干预对持续性中-重度变应性鼻炎的治疗效果如何。方法将符合入选标准的60例持续性中-重度变应性鼻炎患者随机分为对照组、研究组共2组,对照组仅给予单纯药物治疗,研究组在给予与对照组相同药物治疗的基础上,加以心理干预,心理干预选用认知行为疗法,以上两组均治疗12周,并于治疗前、治疗后均采用SAS、SDS、RQLQ三项量表评分,以评估患者治疗前后的焦虑、抑郁状态,以及生活质量变化并进行统计学分析。结果对照组治疗后SAS、SDS评分(50.57±3.64、52.77±5.11)均分别低于治疗前(55.63±5.42、59.57±6.23),差异具有统计学意义(P0.05)。研究组治疗后SAS、SDS评分(45.83±3.97、46.03±3.21)均分别低于治疗前(56.20±3.81、58.53±5.16),差异具有统计学意义(P0.05)。且研究组治疗后SAS、SDS评分(45.83±3.97、46.03±3.21)较对照组(50.57±3.64、52.77±5.11)更低,差异具有统计学意义(P0.05)。对照组治疗后RQLQ各维度评分(7.13±1.28、3.77±0.90、15.90±1.69、5.43±1.94、7.03±1.35、6.03±1.35、7.10±1.09)均分别低于治疗前(11.97±1.54、6.73±1.34、24.30±2.55、10.83±1.91、13.93±2.13、9.77±1.70、11.20±2.06),差异具有统计学意义(P0.05)。研究组治疗后RQLQ各维度评分(6.67±1.45、2.87±0.78、12.47±1.63、5.80±1.09、6.43±1.13、5.70±1.15、5.73±1.46)均分别低于治疗前(11.93±1.28、7.03±1.30、23.73±2.70、11.23±2.14、14.53±2.30、9.33±1.56、11.37±1.88),差异具有统计学意义(P0.05)。经两种不同方案治疗后,在睡眠、非鼻/眼症状、情感3个维度评分中,研究组(2.87±0.78、12.47±1.63、5.73±1.46)均低于对照组(3.77±0.90、15.90±1.69、7.10±1.09),差异具有统计学意义(P0.05)。而研究组的日常生活、实际问题、鼻部症状、眼部症状4个维度评分(6.67±1.45、5.80±1.09、6.43±1.13、5.70±1.15)与对照组(7.13±1.28、5.43±1.94、7.03±1.35、6.03±1.35)的差异无统计学意义(P0.05)。结论1、药物治疗、药物治疗加以心理干预这两种治疗方案均能减轻持续性中-重度AR患者的焦虑、抑郁状态,改善其生活质量。2、从改善持续性中-重度AR患者的精神心理紊乱以及生活质量的疗效看来,在药物治疗的基础上加以心理干预优于单纯使用药物治疗。
[Abstract]:Objective to observe the therapeutic effect of psychological intervention on persistent moderate to severe allergic rhinitis. Methods Sixty patients with persistent moderate to severe allergic rhinitis were randomly divided into control group and control group. The control group was only given simple drug treatment. The study group was given psychological intervention on the basis of the same drug treatment as the control group, and cognitive behavioral therapy was used for psychological intervention. Both groups were treated for 12 weeks, and all of them were scored by SAS,SDS,RQLQ before and after treatment. The changes of anxiety, depression and quality of life before and after treatment were evaluated and statistically analyzed. Results after treatment, the SAS,SDS scores of the control group (50.57 卤3.64, 52.77 卤5.11) were significantly lower than those before treatment (5563 卤5.42, 59.57 卤6.23), and the difference was statistically significant (P 0.05). The SAS,SDS scores of the study group after treatment (45.83 卤3.97, 46.03 卤3.21) were lower than those before treatment (56.20 卤3.81, 58.53 卤5.16), the difference was statistically significant (P 0.05). The SAS,SDS score of the study group (45.83 卤3.97, 46.03 卤3.21) was lower than that of the control group (50.57 卤3.64, 52.77 卤5.11), the difference was statistically significant (P 0.05). After treatment, the scores of RQLQ in the control group (7.13 卤1.28, 3.77 卤0.90, 15.90 卤1.69, 5.43 卤1.94, 7.03 卤1.35, 6.03 卤1.35, 7.10 卤1.09) were significantly lower than those before treatment (11.97 卤1.54, 6.73 卤1.34, 10.83 卤1.91, 13.93 卤2.13, 9.77 卤1.70, 11.20 卤2.06). After treatment, the scores of RQLQ in the study group (6.67 卤1.45,2.87 卤0.78, 12.47 卤1.63, 5.80 卤1.09, 6.43 卤1.13, 5.70 卤1.15, 5.73 卤1.46) were significantly lower than those before treatment (11.93 卤1.28, 7.03 卤1.30, 23.73 卤2.70, 11.23 卤2.14, 14.53 卤2.30, 9.33 卤1.56, 11.37 卤1.88). After treatment with two different regimens, the scores of sleep, non-nasal / eye symptoms and emotion in the study group (2.87 卤0.78, 12.47 卤1.63, 5.73 卤1.46) were significantly lower than those in the control group (3.77 卤0.90, 15.90 卤1.69, 7.10 卤1.09) (P 0.05). However, there was no significant difference in daily life, practical problems, nasal symptoms and eye symptoms between the study group and the control group (6.67 卤1.45, 5.80 卤1.09, 6.43 卤1.13, 5.70 卤1.15) and the control group (7.13 卤1.28, 5.43 卤1.94, 7.03 卤1.35, 6.03 卤1.35) (P 0.05). Conclusion 1. Drug therapy with psychological intervention can reduce anxiety, depression and improve the quality of life of patients with persistent moderate to severe AR. 2. From the point of view of improving the mental and psychological disorder and quality of life of patients with persistent moderate to severe AR, psychological intervention on the basis of drug treatment is superior to drug therapy alone.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R765.21

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