阻塞性睡眠呼吸暂停低通气综合征患者的高刺激率ABR的临床分析

发布时间：2019-07-03 17:00

【摘要】：目的探讨阻塞性睡眠呼吸暂停低通气综合征患者高刺激率ABR和常规刺激率ABR的临床价值及其与间歇性低氧的关系。方法对58例(116耳)OSAHS患者及正常成年人分别进行11次/秒及51次"秒刺激率的听性脑干反应(ABR)测试,比较组间结果。结果 11次"秒刺激率ABR,OSAHS组双耳的波I潜伏期(1.51±0.13ms)较对照组(1.33±0.07ms)延长;波V潜伏期(5.65±0.23ms)较对照组(5.53±0.23ms)延长;在51次/s刺激率下,患者组双耳的Ⅰ波潜伏期、Ⅴ波潜伏期均比正常人延长,(1.64±0.12ms)较对照组(1.44±0.06ms)延长;波V潜伏期(5.92±0.26ms)较对照组(5.80±0.18ms)延长;有统计学意义(P0.05)。而在两种刺激率下,两组人群双耳的Ⅰ~Ⅴ波间期、波间期差值之间的差异均无统计学意义(P0.05)。结论高刺激率ABR可发现中度及重度OSAHS患者耳蜗功能的损伤。
[Abstract]:Objective To study the clinical value of ABR and the normal stimulation rate ABR in patients with obstructive sleep apnea-hypopnea syndrome and its relationship with intermittent hypoxia. Methods Fifty-eight (116 ears) OSAHS patients and normal adults were treated respectively for 11 times/ second and 51 "The auditory brainstem response (ABR) test of the second stimulation rate was compared between the groups. Results 11"-second stimulation (ABR). The latency (1.51-0.13 ms) in the ears of the OSAHS group was longer than that in the control group (1.33-0.07 ms), and the latency of the wave V (5.65-0.23 ms) was longer than that in the control group (5.53-0.23 ms). The latency of I-wave and V-wave in the two ears of the patient group was longer than that of the control group (1.44-0.06 ms) at the 51/ s stimulation rate, and the latency of the wave V (5.92-0.26ms) was longer than that of the control group (5.80-0.18ms), and the latency of the wave-V (5.92-0.26ms) was longer than that of the control group (5.80-0.18ms), and there was a significant difference (P0.05). At the two stimulation rates, there was no significant difference between the first and fifth wave intervals of the two groups (P0.05). Conclusion The high stimulation rate ABR can detect the damage of the cochlear function in the patients with moderate and severe OSAHS.
【作者单位】：清华大学附属北京清华长庚医院耳鼻咽喉头颈外科;清华大学校医院耳鼻咽喉科;秦皇岛市第一医院过敏反应科;
【基金】：北京市医院管理局培育计划(PX2016031) 北京清华长庚医院精准基金计划(12015C4008)共同资助~~
【分类号】：R766

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