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CCR7/p-ERK1/2/VEGF signaling promotes retinal neovasculariza

发布时间:2022-09-28 13:10
  AIM: To investigate the role of CCR7/p-ERK1/2/VEGF signaling in the mouse model of oxygen-induced retinopathy(OIR). METHODS: Neonatal C57BL/6J mice were evenly randomized into four groups: normoxia, OIR, OIR control(treated with scramble si RNA), and OIR treated(treated with CCR7 siRNA). Normoxia group was not specially handled. Postnatal day 7(P7) mice in the OIR group were exposed to 75%±5% oxygen for 5d(P7-P12) and then maintained under normoxic conditions for 5d(P12-P17). Mice in the OIR con... 

【文章页数】:8 页

【文章目录】:
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION


【参考文献】:
期刊论文
[1]CCR7和VEGF在缺氧时视网膜血管内皮细胞中的表达及意义[J]. 底煜,陈晓隆,王爱媛.  国际眼科杂志. 2015(03)



本文编号:3681721

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