常规清洗消毒对胃镜HBV污染的清除效果

发布时间：2018-01-19 22:21

本文关键词： 乙型肝炎表面抗原 HBsAg 内镜检查黏膜损伤清洗消毒乙型肝炎病毒　出处：《中国感染控制杂志》2016年05期 　论文类型：期刊论文

【摘要】：目的了解常规消毒方法对乙型肝炎表面抗原(HBsAg)阳性患者使用过的胃镜乙型肝炎病毒(HBV)污染的清除情况。方法检测2014年12月1—31日于某院行胃镜检查的HBsAg阳性患者使用后的胃镜,根据检查时患者有无黏膜损伤分为黏膜损伤组和黏膜完整组,分别于初洗前、初洗后、消毒后进行3次采样,进行HBsAg、HBV-DNA定量检测。结果黏膜损伤组胃镜初洗前HBsAg检测阳性率为93.33%(28/30)、HBV-DNA定量检测阳性率为53.33%(16/30),黏膜完整组初洗前HBsAg定量检测阳性率为80.00%(24/30)、HBV-DNA定量检测阳性率为20.00%(6/30);初洗前两组HBV-DNA阳性率比较差异有统计学意义(P0.05);初洗后仅黏膜损伤组HBsAg阳性2例(6.67%),余均为阴性;消毒后两组HBsAg与HBV-DNA检测结果均为阴性。结论 HBsAg阳性患者使用后的胃镜可以通过规范的常规清洗和消毒达到消毒效果。
[Abstract]:Objective to investigate the efficacy of routine disinfection methods in gastroscope hepatitis B virus (HBV) infection in patients with HBsAg HBsAg positive. Methods Gastroscopy was used by HBsAg positive patients in a hospital from December 2014 to 31. The patients were divided into mucosal injury group and mucosal integrity group according to whether they had mucosal injury at the time of examination. The patients were sampled three times before and after first washing and disinfection for HBsAg. Results the positive rate of HBsAg was 93.33 / 30 before the first washing of gastroscope in the mucosal injury group. The positive rate of HBV-DNA quantitative detection was 53.33% and 16 / 30% respectively. The positive rate of HBsAg quantitative detection before first washing was 80.000 / 24 / 30 in the mucosal intact group. The positive rate of HBV-DNA quantitative detection was 20.00% 30%. There was significant difference in HBV-DNA positive rate between the two groups before the first wash (P 0.05). Only 2 cases of HBsAg were positive in the group of mucosal injury after first washing, and the rest were negative. The results of HBsAg and HBV-DNA were negative in both groups after disinfection. Conclusion Gastroscope of HBsAg positive patients can be disinfected by standard routine cleaning and disinfection.
【作者单位】：上海东方肝胆外科医院;
【分类号】：R573;R512.62
【正文快照】： 我国为乙型肝炎病毒(hepatitis B virus,HBV)感染高发区,HBV携带者超过1亿[1]。本院为肝胆专科医院,接受胃镜检查患者中乙型肝炎表面抗原(HBsAg)阳性者可达60%~70%。因HBV可通过血液和体液传播[2],胃镜检查不可避免会引起黏膜损伤,存在HBV交叉感染风险,导致非HBV感染者行胃镜

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