肝硬化合并上消化道出血患者医院感染的相关因素分析

发布时间：2018-03-02 13:20

本文选题：肝硬化　切入点：上消化道出血　出处：《中华医院感染学杂志》2017年14期 　论文类型：期刊论文

【摘要】：目的探讨肝硬化并上消化道出血患者医院感染的危险因素,为临床防治策略的制定提供参考依据。方法回顾性分析医院2013年1月-2016年1月期间收治的350例肝硬化并上消化道出血患者的临床资料;分析医院感染的发生率、病原菌类型以及感染部位分布情况;通过多因素Logistic回归分析归纳肝硬化并上消化道出血患者发生医院感染的危险因素。结果本研究医院感染的发生率为29.14%,培养出致病菌46株,其中革兰阴性菌24株、占52.17%,革兰阳性菌13株、占28.26%,真菌9株、占19.57%。呼吸道感染最为常见,有40例、占39.22%,其次为腹腔感染31例、占30.39%;多因素logistic分析结果显示,年龄大、血红蛋白水平低、血清蛋白水平低、Child-pugh评分高、未预防性应用抗菌药物、有腹水、未使用三腔两囊管压迫止血以及未使用胃镜套扎止血是肝硬化并上消化道出血医院感染的危险因素(P0.05)。结论肝硬化并上消化道出血患者医院感染发生率高,临床应加强预防措施,降低患者发生医院感染的风险。
[Abstract]:Objective to investigate the risk factors of nosocomial infection in patients with liver cirrhosis and upper gastrointestinal hemorrhage. Methods the clinical data of 350 patients with liver cirrhosis and upper gastrointestinal hemorrhage from January 2013 to January 2016 were retrospectively analyzed, and the incidence of nosocomial infection was analyzed. The risk factors of nosocomial infection in patients with liver cirrhosis and upper gastrointestinal bleeding were summarized by multivariate Logistic regression analysis. Results the incidence of nosocomial infection was 29.14, and 46 strains of pathogenic bacteria were cultured. There were 24 Gram-negative bacteria (52.17g), 13 Gram-positive bacteria (28.26%), 9 fungi (19.57%). Respiratory tract infection (40 cases, 39.22%) was the most common, followed by intraperitoneal infection (31 cases, 30.39%). Low hemoglobin level, low serum protein level, high Child-pugh score, no prophylactic use of antimicrobial agents, ascites, The risk factors of nosocomial infection in patients with liver cirrhosis and upper gastrointestinal bleeding were P0.05. Conclusion the incidence of nosocomial infection in patients with liver cirrhosis and upper gastrointestinal bleeding is high, and the preventive measures should be strengthened in clinic. Reduce the risk of nosocomial infection.
【作者单位】：郑州大学附属洛阳中心医院消化内科;
【分类号】：R573.2;R575.2

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