双能量能谱CT碘含量测定对急性胰腺炎的诊断

发布时间：2018-03-07 21:50

本文选题：胰腺炎　切入点：急性病　出处：《中国医学影像学杂志》2015年10期 　论文类型：期刊论文

【摘要】：目的应用双能量能谱CT物质定量分析技术对急性胰腺炎(AP)的碘含量进行测定,探讨碘含量与其临床严重程度的相关性,为临床评估AP严重程度提供有效的影像检查手段。资料与方法回顾性分析经临床确诊为AP的60例患者(AP组)以及因非胰腺疾病行CT检查且胰腺正常的30例患者(对照组),测量并比较胰腺增强扫描动脉期及门静脉期碘物质浓度及标准化碘浓度(NIC)。结果 AP组增强扫描动脉期及门静脉期的碘浓度值与NIC均低于对照组(P0.05、P0.001)。根据Ranson评分标准,AP组中24例轻症,20例中症,16例重症。随着Ranson严重程度增加,碘物质浓度及NIC下降,3组动脉期及门静脉期碘浓度值差异有统计学意义(F动脉期=8.776,P0.01;F门静脉期=4.019,P0.05),NIC差异有统计学意义(F动脉期=12.700,P0.001;F门静脉期=8.732,P0.01)。轻症组动脉期及门静脉期碘浓度值与NIC均高于中症组(P0.05);重症组动脉期及门静脉期碘浓度值、动脉期NIC均低于中症组(P0.05)。结论双能量能谱CT碘含量测定可以定量分析胰腺炎的血流动力学改变,对判断各级胰腺炎微循环的变化具有重要价值。
[Abstract]:Objective to study the correlation between iodine content and clinical severity of acute pancreatitis (AP) by means of quantitative analysis of substance with dual energy spectrum CT. To provide an effective imaging method for clinical assessment of AP severity. Data and methods A retrospective analysis of 60 patients with AP and 30 patients with normal pancreas due to non-pancreatic diseases (. In the control group, iodine concentration and standardized iodine concentration were measured and compared in arterial phase and portal phase. Results iodine concentration and NIC in enhanced scanning arterial phase and portal vein phase in AP group were lower than those in control group (P 0.05 P 0.001). In the AP group, there were 24 cases of mild disease and 20 cases of severe disease. The severity of Ranson increased with the increase of the severity of Ranson. There were significant differences in iodine concentration and iodine concentration in arterial phase and portal vein phase in the three groups with decreased NIC. There were significant differences in the arterial phase and portal vein phase between the three groups. There were significant differences in the arterial phase and portal vein phase in the patients with mild disease. There were significant differences in the arterial phase and portal vein phase in the F artery phase and in the F artery phase and in the portal vein phase and the arterial phase and the portal vein phase in the patients with mild disease. The arterial phase and the portal vein phase in the patients with mild disease were 8.732P0.01.There was significant difference in the concentration of iodine and iodine. Iodine concentration and NIC were higher than those in moderate disease group (P 0.05), while in severe group, iodine concentration in arterial phase and portal vein phase was higher than that in severe group. Conclusion the measurement of iodine content in dual-energy spectrum CT can quantitatively analyze the hemodynamic changes of pancreatitis, and it is of great value to judge the changes of microcirculation in all levels of pancreatitis.
【作者单位】：安徽医科大学附属省立医院影像科;安徽医科大学第一附属医院放射科;
【基金】：国家自然科学基金青年科学基金项目(81501468) 安徽省科技厅公益性技术应用研究联动计划项目(1501ld04028)
【分类号】：R576;R816.5

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