普芦卡必利治疗功能性便秘的临床观察

发布时间：2018-03-12 17:45

本文选题：功能性便秘　切入点：普芦卡必利　出处：《中国药房》2015年20期 　论文类型：期刊论文

【摘要】：目的:观察普芦卡必利治疗功能性便秘的疗效及安全性。方法:选取功能性便秘女性患者87例,给予普芦卡必利2 mg,qd,总疗程为4周,采用前瞻性自身对照研究,观察患者治疗前后排便次数、大便性状、排便困难程度的变化情况以及服药期间出现的相关不良反应。结果:治疗后患者每周大便次数逐渐增加,大便性状逐渐趋于正常,排便费力情况明显缓解。各观察指标在治疗前后比较差异均有统计学意义(P0.01)。研究过程中未见严重不良反应发生。结论:普芦卡必利治疗功能性便秘安全、有效。
[Abstract]:Objective: to observe the efficacy and safety of prucapride in the treatment of functional constipation. The changes of defecation frequency, defecation character, defecation difficulty and related adverse reactions during the treatment were observed. Results: after treatment, the defecation frequency increased gradually and the defecation character became normal. The defecation effort was alleviated obviously. The differences of observed indexes before and after treatment were statistically significant (P 0.01). No serious adverse reactions occurred during the study. Conclusion: prucapride is safe and effective in the treatment of functional constipation.
【作者单位】：重庆医科大学附属第一医院消化内科;
【分类号】：R574.62

【参考文献】