持续高容量血液滤过联合胸腹腔引流在重症急性胰腺炎治疗中的应用

发布时间：2018-03-27 19:15

  本文选题：急性胰腺炎　切入点：持续高容量血液滤过　出处：《山东医药》2015年35期

【摘要】：目的观察持续高容量血液滤过(HFD)联合胸腹腔引流在重症急性胰腺炎(SAP)治疗中的应用效果。方法 51例SAP患者随机分为观察组36例和对照组15例,两组均采用基础治疗,观察组在此基础上采用HFD联合胸腹腔引流。采用ELISA法检测两组IL-6,乳胶增强免疫法检测C反应蛋白(CRP),记录腹痛消失、腹胀缓解时间及CT严重程度评分、急性生理学和慢性健康状况评分(APACHEⅡ评分)。结果与同组治疗前比较,两组治疗3 d IL-6、CRP水平降低(P均0.05);与对照组比较,观察组治疗3 d IL-6、CRP水平降低(P均0.05)。与对照组比较,观察组腹痛持续、腹胀缓解时间短(P均0.05)。与同组治疗前比较,两组治疗3、14 d CT严重程度评分及APACHEⅡ评分降低(P均0.05);与对照组比较,观察组治疗3、14 d CT严重程度评分及APACHEⅡ评分降低(P均0.05)。结论 HFD联合胸腹腔液体引流用于SAP治疗效果较好。
[Abstract]:Objective to observe the effect of continuous high volume hemofiltration combined with chest and abdominal drainage in the treatment of severe acute pancreatitis (SAP). Methods 51 patients with SAP were randomly divided into observation group (n = 36) and control group (n = 15). On this basis, HFD combined with chest and abdominal drainage was used in the observation group, IL-6 was detected by ELISA method, C-reactive protein (CRP) was detected by emulsion enhanced immunoassay, abdominal pain disappeared, abdominal distension remission time and CT severity score were recorded. Results compared with the same group before treatment, the levels of IL-6 and CRP in the two groups decreased by 0.05% on the 3rd day after treatment, compared with the control group, the levels of IL-6 and CRP in the observation group were lower than those in the control group on the 3rd day after treatment, and the levels of IL-6 and CRP in the observation group were lower than those in the control group, and the levels of IL-6 and CRP in the observation group were lower than those in the control group. Compared with the control group, the CT severity score and APACHE 鈪，

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