中西医结合治疗慢性萎缩性胃炎合并幽门螺杆菌感染的临床疗效观察

发布时间：2018-03-31 18:39

本文选题：慢性萎缩性胃炎　切入点：幽门螺杆菌　出处：《重庆医学》2017年29期

【摘要】：目的观察中西医结合治疗慢性萎缩性胃炎合并幽门螺杆菌感染的临床疗效。方法选取2015年3月至2016年7月于该院就诊的60例慢性萎缩性胃炎合并幽门螺杆菌感染患者,分为对照组与观察组,各30例。对照组给予三联疗法治疗,观察组给予中药联合三联疗法治疗。治疗6个月后,比较两组患者的临床症状、病理特征及疗效。结果治疗6个月后,观察组在胃黏膜萎缩、肠上皮增生改善的有效率高于对照组(P0.05);而两组在不典型增生改善的有效率比较,差异无统计学意义(P0.05)。观察组在改善胃痛、胃胀两个临床症状的有效率优于对照组(P0.05);在改善嘈杂泛酸、纳呆少食两个临床症状的有效率比较,差异无统计学意义(P0.05)。观察组幽门螺杆菌转阴率为83.33%;对照组为70.00%,两组比较差异无统计学意义(P0.05)。结论中西医结合治疗慢性萎缩性胃炎合并幽门螺杆菌感染比单纯三联疗法具有更好的临床效果。
[Abstract]:Objective to observe the clinical effect of combined traditional Chinese and western medicine on chronic atrophic gastritis with Helicobacter pylori infection.Methods 60 patients with chronic atrophic gastritis complicated with Helicobacter pylori infection from March 2015 to July 2016 were divided into control group and observation group with 30 cases each.The control group was treated with triple therapy and the observation group with traditional Chinese medicine combined with triple therapy.After 6 months of treatment, the clinical symptoms, pathological features and efficacy of the two groups were compared.Results after 6 months of treatment, the effective rate of gastric mucosal atrophy and intestinal epithelial hyperplasia in the observation group was higher than that in the control group (P 0.05), but there was no significant difference between the two groups in the improvement rate of atypical hyperplasia.In the observation group, the effective rate of the two clinical symptoms of stomach pain and stomach distention was better than that of the control group (P 0.05), but there was no significant difference between the two clinical symptoms in improving pantothenic acid and eating less food than in the control group (P 0.05).The negative conversion rate of Helicobacter pylori in the observation group was 83.33 and that in the control group was 70.00.The difference between the two groups was not statistically significant (P 0.05).Conclusion the treatment of chronic atrophic gastritis with Helicobacter pylori infection is more effective than triple therapy.
【作者单位】：石河子大学医学院第一附属医院中医科;
【分类号】：R573.32

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