白云机场口岸从业人员甲型和戊型肝炎IgM分析

发布时间：2018-04-15 04:02

本文选题：从业人员 + 甲肝IgM　；参考：《中国公共卫生》2015年07期

【摘要】：目的比较分析口岸从业人员甲型和戊型肝炎病毒IgM抗体水平,了解广州白云机场口岸从业人员HAV、HEV感染状况。方法采用酶联免疫法(ELISA)对2010年3月—2013年12月共35 995份口岸从业人员体检血清样本进行抗HAV-IgM和抗HEV-IgM检测,并采用χ2检验和直线回归分析等方法对阳性结果进行统计分析。结果 HAV-IgM阳性率为0.328%(118/35 995),HEV-IgM阳性率为0.253%(91/35 995);HAV-IgM阳性率有季节性差异(χ2=21.86,P0.001),夏、秋季高,春季最低;HEV-IgM阳性率无季节性差异(χ2=3.67,P=0.299);直线回归分析认为HAV-IgM阳性率随着年龄的增加而增加(t=4.360,P=0.049);而HEV-IgM阳性率与年龄未呈明显的线性趋势(t=2.034,P=0.179);HAV-IgM阳性率(χ2=0.023,P=0.880)、HEV-IgM阳性率(χ2=1.641,P=0.200)在性别方面均无统计学差异;结论广州白云机场口岸从业人员HAV、HEV感染率较高,有明显的季节性,且HAV-IgM阳性率随年龄的增加而增加;HEV-IgM阳性率与季节、年龄、性别无关,四季皆可发病,人群普遍易感。
[Abstract]:Objective to compare and analyze the level of hepatitis A and E virus IgM antibody in port workers and to understand the infection status of hepatitis A virus in Guangzhou Baiyun airport.Methods from March 2010 to December 2013, 35 995 serum samples from port employees were tested for anti HAV-IgM and anti HEV-IgM by enzyme linked immunosorbent assay (Elisa). The positive results were statistically analyzed by 蠂 2 test and linear regression analysis.Results the positive rate of HAV-IgM was 0.328% and the positive rate of HEV-IgM was 0.258 / 35,995. there was seasonal difference in the positive rate of HAV-IgM between 0.253R and 91R / 35995C (蠂 ~ 2 = 21.86U P 0.001), high in summer and autumn, higher in summer and autumn, higher in summer and autumn, higher in summer, higher in summer, higher in autumn, and higher in summer and autumn.There was no seasonal difference in the lowest positive rate of HEV-IgM in spring (蠂 ~ 2 ~ 2 ~ (3.67) P ~ (0.299)). The linear regression analysis showed that the positive rate of HAV-IgM increased with the increase of age, but the positive rate of HEV-IgM had no significant linear trend with age (蠂 ~ (0.023) P ~ (0.880) P ~ (0.200)). There was no significant difference in the positive rate of HEV-IgM and age (蠂 ~ 21.641P ~ (0.200)). The positive rate of HEV-IgM was not significantly different from that of age (蠂 ~ 21.641P ~ (0.200)), but there was no significant difference between the two groups in the positive rate of HEV-IgM (蠂 ~ 2 = 3.67) (蠂 ~ 21.641P ~ (0.200)).Conclusion the infection rate of HAV-IgM in Guangzhou Baiyun Airport port workers is high and seasonal, and the positive rate of HAV-IgM increases with the increase of age. The positive rate of HEV-IgM is not related to season, age and sex.
【作者单位】：广州机场出入境检验检疫局综合实验室;
【分类号】：R512.6

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