早期肠内营养联合谷氨酰胺对老年重症急性胰腺炎营养状况的影响

发布时间：2018-04-18 00:17

  本文选题：重症急性胰腺炎 + 谷氨酰胺　； 参考：《中国老年学杂志》2015年12期

【摘要】：目的探讨早期肠内营养(EN)联合谷氨酰胺对老年重症急性胰腺炎(SAP)营养状况的影响。方法将该院收治的90例老年SAP患者随机分为观察组与对照组各45例,在基础治疗的基础上,观察组给予早期EN联合谷氨酰胺营养干预支持,对照组给予完全胃肠外营养(TPN)。观察并比较两组患者入院时、营养支持7、14 d后的血淀粉酶、尿淀粉酶、急性生理学及慢性健康状况(APACHE-Ⅱ)评分、Ranson评分及血清白蛋白(ALB)、血清前白蛋白(PA)、转铁蛋白(TRF)及体重变化情况;并比较两组患者平均住院天数及并发症发生率。结果两组患者治疗7、14 d后,血淀粉酶、尿淀粉酶、APACHE-Ⅱ评分、Ranson评分均较入院时显著下降(P0.05);观察组患者治疗7、14 d后上述指标明显低于对照组同期(P0.05);观察组患者治疗7、14 d后ALB、PA、TRF及体重均高于对照组(P0.05);观察组平均住院天数显著短于对照组,其并发症发生率低于对照组。结论早期EN联合谷氨酰胺营养支持干预较TPN在治疗老年SAP中能更有效地缓解机体高分解代谢,明显改善患者营养状况,有效减少并发症发生,值得临床重视。
[Abstract]:Objective to investigate the effect of early enteral nutrition (en) combined with glutamine on the nutritional status of elderly patients with severe acute pancreatitis (SAP).Methods 90 elderly patients with SAP were randomly divided into two groups: the observation group (n = 45) and the control group (n = 45). On the basis of basic treatment, the observation group was given early en combined with glutamine nutrition intervention support, and the control group was given complete parenteral nutrition.The serum amylase and urine amylase were observed and compared between the two groups after 7d of nutrition support.Acute Physiology and chronic Health status (APACHE- 鈪，

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