十二指肠病变内镜黏膜切除术后钛夹闭合创面的价值评价

发布时间：2018-04-30 15:07

本文选题：内镜黏膜切除术 + 十二指肠　；参考：《中国内镜杂志》2015年08期

【摘要】：目的评估非壶腹部十二指肠病变内镜黏膜切除术(EMR)后钛夹闭合创面的临床价值。方法回顾性分析54例十二指肠黏膜病变EMR术后患者,根据是否行钛夹闭合创面分为钛夹组(n=25)和对照组(n=29),比较两组患者的EMR术后迟发性出血率及术后4和6周的溃疡分期及瘢痕愈合率。结果钛夹组患者无术后迟发性出血发生,对照组有6例,钛夹组术后迟发性出血率显著低于对照组(P0.05)。钛夹组术后4和6周的瘢痕期(S1)期溃疡瘢痕愈合率分别为88.0%和100.0%,分别显著高于同期对照组的溃疡瘢痕愈合率55.2%和79.3%(P0.05)。对两组的溃疡分期比较,钛夹组患者术后4和6周的整体溃疡愈合质量均显著高于对照组患者(P0.05)。结论金属钛夹闭合十二指肠黏膜病变EMR术后创面可显著降低术后迟发性出血的风险,并可提高医源性溃疡的愈合速度和愈合质量。
[Abstract]:Objective to evaluate the clinical value of titanium clip wound closure after endoscopic mucosal resection (EMR) for non-ampullary duodenal lesions. Methods 54 cases of duodenal mucosal lesions after EMR were retrospectively analyzed. According to whether the wound was closed with titanium clip or not, the patients were divided into two groups: the titanium clip group (n = 25) and the control group (n = 29). The rate of delayed bleeding after EMR, the stage of ulcer 4 and 6 weeks after operation and the rate of scar healing were compared between the two groups. Results there were no delayed bleeding in the titanium clip group and 6 cases in the control group. The rate of delayed hemorrhage in the titanium clip group was significantly lower than that in the control group (P 0.05). The rate of scar healing in the titanium clip group at 4 and 6 weeks after operation was 88.0% and 100.0% respectively, which was significantly higher than that in the control group (55.2% and 79.3% respectively). The overall ulcer healing quality in the titanium clip group was significantly higher than that in the control group at 4 and 6 weeks after operation. Conclusion closure of duodenal mucosal lesions with titanium clip can significantly reduce the risk of delayed bleeding after EMR and improve the healing speed and healing quality of iatrogenic ulcer.
【作者单位】：南京军区福州总医院消化内科;
【分类号】：R574.51

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