重症急性胰腺炎患者继发胰腺感染的危险因素研究

发布时间：2018-05-03 21:13

  本文选题：胰腺感染 + 重症急性胰腺炎　； 参考：《中华医院感染学杂志》2015年09期

【摘要】：目的研究重症急性胰腺炎(SAP)继发胰腺感染的危险因素,为临床诊治提供参考。方法选取2012年6月-2013年12月医院收治的SAP患者102例为研究对象,根据是否继发胰腺感染将其分为感染组38例,未感染组64例;对胰腺感染的危险因素进行分析,采用SPSS17.0软件对数据进行统计分析。结果胰腺感染率为37.25%;感染组共培养出69株病原菌,其中革兰阴性菌占73.91%;革兰阳性菌占26.09%;革兰阴性杆菌对亚胺培南、美罗培南较敏感,敏感率为100.00%、92.11%;革兰阳性菌对万古霉素敏感,敏感率为100.00%;两组血钙(Ca2+)浓度、APACHEⅡ评分、糖尿病、低氧血症、胰腺坏死分期、多器官功能障碍综合征(MODS)、胃肠功能障碍、机械通气时间、肠外营养时间比较差异有统计学意义(P0.05);logistic回归分析显示,低血Ca2+、合并糖尿病、MODS、Ⅲ期胰腺坏死、胃肠功能障碍≥7d是SAP继发胰腺感染的独立危险因素。结论 SAP继发胰腺感染的危险因素复杂,对合并糖尿病、MODS、胰腺坏死患者采取积极预防措施,降低胰腺感染风险。
[Abstract]:Objective to study the risk factors of pancreatic infection secondary to severe acute pancreatitis (SAP) and to provide reference for clinical diagnosis and treatment. Methods 102 patients with SAP admitted in hospital from June 2012 to December 2013 were divided into infection group (n = 38) and uninfected group (n = 64) according to whether they had secondary pancreatic infection, and the risk factors of pancreatic infection were analyzed. The data were analyzed by SPSS17.0 software. Results the infection rate of pancreas was 37.25. 69 pathogenic bacteria were cultured in the infection group, of which 73.91 were Gram-negative bacteria, 26.09 were Gram-positive bacteria. Gram-negative bacilli were sensitive to imipenem and meropenem with a sensitivity rate of 100.00g / 92.110.Gram-positive bacteria were sensitive to vancomycin. The sensitivity rate was 100.00. the serum calcium concentration in the two groups was evaluated by Apache 鈪，

本文编号：1840104