铝碳酸镁联合奥美拉唑治疗胃溃疡48例临床观察

发布时间：2018-05-04 15:12

本文选题：胃溃疡 + 铝碳酸镁　；参考：《中国实用内科杂志》2015年S1期

【摘要】：目的分析铝碳酸镁联合奥美拉唑治疗胃溃疡的临床效果。方法回顾性分析2013年10月至2014年10月新疆昌吉市第二人民医院收治的96例胃溃疡患者的临床资料,按照不同给药方法分为观察组与对照组,每组48例。对照组予奥美拉唑治疗,观察组在其基础上加予铝碳酸镁治疗,比较两组患者临床疗效、不良反应及复发情况。结果观察组临床总有效率93.75%高于对照组的77.08%,不良反应总发生率4.17%低于对照组的20.83%,且随访3个月后的复发率2.08%少于对照组的18.75%,差异均具有统计学意义(P0.05)。结论铝碳酸镁联合奥美拉唑治疗胃溃疡的临床效果显著,有助于愈合患者溃疡创面并保护胃黏膜,且安全性较高、复发率较低,值得积极推广。
[Abstract]:Objective to analyze the clinical effect of magnesium bicarbonate combined with omeprazole in the treatment of gastric ulcer. Methods the clinical data of 96 patients with gastric ulcer treated in the second people's Hospital of Changji City, Xinjiang from October 2013 to October 2014 were retrospectively analyzed. According to different administration methods, they were divided into observation group and control group with 48 cases in each group. The control group was treated with omeprazole, the observation group was treated with magnesium bicarbonate on the basis of omeprazole, and the clinical efficacy, adverse reaction and relapse were compared between the two groups. Results the total effective rate of the observation group was 93.75% higher than that of the control group (77.08%), and the total incidence of adverse reactions was 4.17% lower than that of the control group (20.83%). The recurrence rate of the observation group was 2.08% after 3 months follow-up compared with 18.7575% of the control group. The difference was statistically significant (P 0.05). Conclusion the clinical effect of magnesium bicarbonate combined with omeprazole in the treatment of gastric ulcer is remarkable, which is helpful for healing the ulcer wound and protecting gastric mucosa. It is safe and has a low recurrence rate, which is worthy of active promotion.
【作者单位】：新疆昌吉市第二人民医院消化内科;
【分类号】：R573.1

【参考文献】