联动成像内镜与白光内镜对胃黏膜感染幽门螺杆菌的诊断价值比较

发布时间：2018-05-13 02:44

本文选题：联动成像 + 白光内镜　；参考：《实用医学杂志》2017年14期

【摘要】：目的比较联动成像内镜(LCI)与传统白光内镜对胃黏膜幽门螺杆菌(Hp)感染的诊断价值。方法用白光和LCI模式分别观察胃黏膜,用取色软件测量两种模式下可疑Hp感染区域的红色(R)、绿色(G)、蓝色(B)的组成值,并对可疑部位取活检行病理检测,R/(G+B)比值用于建立预测Hp感染的受试者工作特征曲线(ROC),并计算曲线下面积(AUC)、cut-off值及灵敏度和特异度。结果共纳入47例研究对象,其中维吾尔族23例,平均49岁。共获得91例病理组织,确诊Hp感染44例。LCI模式建立的曲线的AUC为0.616,cut-off值为0.967,灵敏度为0.955,特异度为0.298;白光模式建立的曲线的AUC为0.529,cut-off值为2.638,灵敏度为0.455,特异度为0.766。LCI诊断汉族和维吾尔族Hp感染的AUC分别为0.65、0.549。LCI诊断萎缩性胃炎和非萎缩性胃炎患者Hp感染的AUC分别为0.628、0.603。结论 LCI模式较白光模式诊断胃黏膜Hp感染具有更高的诊断效能,可作为一种客观的内镜下辅助判断胃黏膜Hp感染的定量方法。
[Abstract]:Objective to compare the diagnostic value of combined imaging endoscopy (LCI) and traditional white light endoscopy in the diagnosis of Helicobacter pylori (HP) infection in gastric mucosa. Methods the gastric mucosa was observed by white light and LCI mode, and the composition values of the suspected HP infection areas were measured by color extraction software. The ratio of R- / G to G) was used to establish the operating characteristic curve for predicting HP infection, and the area under the curve was calculated as a cut-off value, sensitivity and specificity. Results A total of 47 subjects were included, 23 of them were Uygur, with an average age of 49 years. 91 cases of pathological tissues were obtained. The AUC value, sensitivity and specificity of the curve established by the LCI model in 44 cases with confirmed HP infection were 0.616 cut-off value 0.967, the sensitivity was 0.955, the specificity was 0.298, the AUC value of the curve established by the white-light model was 0.529 cut-off value was 2.638, the sensitivity was 0.455.The specificity of the curve was 0.766.LCI for the diagnosis of HP infection in Han and Uygur nationalities. The AUC of HP infection in patients with atrophic gastritis and non-atrophic gastritis was 0.628 and 0.603, respectively. Conclusion LCI model is more effective than white light mode in the diagnosis of HP infection in gastric mucosa. It can be used as an objective quantitative method for the diagnosis of HP infection in gastric mucosa under endoscope.
【作者单位】：南方医科大学南方医院;新疆喀什地区第一人民医院;广东药科大学附属第一医院;
【基金】：广东省科技厅资助项目(编号:2016A020212022);广东省科技厅资助项目(编号:2016A020212007) 中国健康促进基金会(横向课题,内镜下诊断幽门螺杆菌感染胃黏膜病变研究)
【分类号】：R573

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