山西省169例布加综合征分析

发布时间：2018-05-13 20:26

本文选题：布加综合征 + 临床特点　；参考：《山西医科大学》2014年硕士论文

【摘要】：目的：分析布加综合征（Budd-Chiari Syndrome,BCS）的临床特点，初步了解该综合征在山西省的分布特征，为临床诊断提供经验，为病因研究提供依据。方法：1.整理山西省169例布加综合征患者的首次入院资料； 2.分析性别、发病年龄、城乡情况、居住地等一般资料； 3.分析主要临床表现、病变类型、肝功能、超声、影像学检查结果及肝穿刺结果等病史资料及首次诊断情况。结果： 1.人群分布特征：BCS各年龄段均有发病，发病年龄范围为5~75岁，平均（37.98±14.27）岁，以青壮年为主；无明显性别差异；城乡差别明显，农村人口明显高于城市；地域差异明显，主要集中在太原（晋中）盆地，与山西省高碘地区分布范围基本相符。 2.分型结果：下腔静脉型101例（59.76%），混合型50例（29.59%），肝静脉型18例（10.65%）。 3.临床表现：乏力、纳差、腹胀、腹痛为就诊主要症状，下肢肿胀、下肢静脉曲张、胸腹壁静脉曲张、肝脾大、腹水为就诊主要体征，各型中上述临床表现出现频率不同。 4.肝功能：肝静脉型与非肝静脉型组间比较ALT、AST、GGT差异有统计学意义。 5.首次诊断情况：临床漏诊、误诊率较高（54.44%），，其中肝静脉型更高（83.33%）。结论：布加综合征临床表现多样，漏诊、误诊现象常见，诊断除参考临床表现外，应结合肝功能、彩超、血管造影结果及城乡、地域特点；肝穿刺活检具有提示诊断价值，尤其对于肝静脉型。
[Abstract]:Objective: to analyze the clinical characteristics of Budd-Chiari Syndromesia syndrome (BCSS), and to understand the distribution of Budd-Chiari Syndrome syndrome in Shanxi Province, to provide experience for clinical diagnosis and to provide evidence for etiological study. Method 1: 1. The first admission data of 169 cases of Budd-Chiari syndrome in Shanxi Province were analyzed. 2. Analysis of gender, age of onset, urban and rural situation, residence and other general data; 3. The main clinical manifestations, pathological types, liver function, ultrasound, imaging findings and liver puncture findings were analyzed. Results: 1. The age range of onset of BCS was 50.75 years (mean 37.98 卤14.27) years. There was no significant difference between male and female, the difference between urban and rural areas was obvious, the rural population was obviously higher than that in urban area, and the regional difference was obvious. Mainly concentrated in Taiyuan (Jinzhong) basin, and the distribution of high-iodine area in Shanxi Province is basically consistent. 2. Results: there were 101 cases of inferior vena cava type with 59.76A, 50 cases of mixed type with 29.59R and 18 cases with hepatic vein type with 10.65m. 3. Clinical manifestations: fatigue, anorexia, abdominal distension, abdominal pain, lower limb swelling, varicose veins of lower extremity, varices of thoracic and abdominal wall, hepatomegaly and ascites were the main signs. 4. Liver function: the difference of GGT between hepatic vein type and non hepatic vein type was statistically significant. 5. The first diagnosis: the misdiagnosis rate was higher than 54.44%, and the hepatic vein type was higher than 83.33%. Conclusion: The clinical manifestations of Budd-Chiari syndrome are diverse, missed diagnosis and misdiagnosis are common. In addition to the reference clinical manifestations, diagnosis should be combined with liver function, color ultrasound, angiographic results, urban and rural, regional characteristics. Especially for hepatic vein type.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R575

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