ω-3鱼油脂肪乳注射液辅助治疗重症急性胰腺炎的疗效及对患者血清肿瘤坏死因子-α和白细胞介素-1β影响的研究

发布时间：2018-05-13 21:02

本文选题：重症急性胰腺炎 + ω-鱼油脂肪乳　；参考：《中国现代医学杂志》2015年19期

【摘要】：目的分析ω-3鱼油脂肪乳注射液辅助治疗重症急性胰腺炎(SAP)的疗效及对患者血清肿瘤坏死因子-α(TNF-α)和白细胞介素-1β(IL-1β)的影响。方法选择在该院接受住院治疗的SAP患者作为研究对象,随机分为接受常规治疗的对照组、接受ω-3鱼油脂肪乳注射液辅助治疗的观察组,比较两组患者的恢复时间及并发症情况、血清相关指标和血清炎症因子水平等差异。结果 1观察组患者的肠道恢复时间、总住院时间均明显短于对照组,住院期间各种并发症发生率显著低于对照组(P0.05);2观察组患者接受治疗后的血清白蛋白水平高于对照组,白细胞总数、中性粒细胞总数、血淀粉酶水平明显低于对照组(P0.05);3观察组患者接受治疗后的TNF-α和IL-1β水平明显低于对照组(P0.05)。结论ω-3鱼油脂肪乳注射液辅助治疗可以有效促进重症急性胰腺炎患者康复,减少并发症发生,降低血清白细胞、血淀粉酶及炎症因子水平。
[Abstract]:Objective to analyze the efficacy of 蠅 -3 fish oil fat emulsion injection in the treatment of severe acute pancreatitis (SAP) and its effect on serum tumor necrosis factor- 伪 (TNF- 伪) and interleukin-1 尾 (IL-1 尾). Methods SAP patients who were hospitalized in the hospital were randomly divided into two groups: the control group treated with routine treatment and the observation group treated with omega-3 fish oil fat emulsion injection. The recovery time and complications of the two groups were compared. Serum related indexes and serum inflammatory factors were different. Results 1 the recovery time and total hospitalization time of the patients in the observation group were significantly shorter than those in the control group, and the incidence of various complications during the hospitalization was significantly lower than that in the control group after treatment, and the level of serum albumin in the observation group was higher than that in the control group. The total leukocyte count, neutrophil count and serum amylase level were significantly lower in the observation group than those in the control group. The levels of TNF- 伪 and IL-1 尾 in the observation group were significantly lower than those in the control group. Conclusion the adjuvant treatment of 蠅 -3 fish oil fat emulsion injection can effectively promote the rehabilitation of patients with severe acute pancreatitis, reduce the incidence of complications and reduce the levels of serum white blood cells, serum amylase and inflammatory factors.
【作者单位】：河南省南阳市中心医院普外科;
【分类号】：R576

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