胃食管反流病患者食管外表现的发生率及危险因素的研究

发布时间：2018-05-14 15:38

本文选题：新疆胃食管反流病 + 食管外表现　；参考：《新疆医科大学》2014年硕士论文

【摘要】：目的：研究新疆胃食管反流病（gastroesophageal reflux disease, GERD）患者食管外表现的发生率及危险因素。方法：调查比较新疆GERD患者三种常见食管外表现（反流性咽喉炎、反流性咳嗽和反流性哮喘）的发生率，分析三种常见食管外表现发生之间的相关性，初步探讨发生食管外表现的危险因素。结果：①新疆GERD患者三种常见食管外表现的总发生率为47.01％，其中反流性咽喉炎的发生率（27.24％）最高，反流性咳嗽（15.67％）次之，反流性哮喘（12.31％）最低；②男性与女性GERD患者三种常见食管外表现的总发生率、反流性咽喉炎、反流性咳嗽和反流性哮喘的发生率均无显著差异。男性反流性咽喉炎的发生率最高，反流性咳嗽次之，反流性哮喘最低。女性反流性咽喉炎的发生率高于反流性咳嗽和反流性哮喘，但反流性咳嗽与反流性哮喘的发生率无显著差异；③维族患者三种食管外表现的总发生率高于汉族、反流性咽喉炎的发生率低于汉族，反流性咳嗽和反流性哮喘的发生率高于汉族。反流性咽喉炎是汉族患者最常见的食管外表现，其发生率高于反流性咳嗽和反流性哮喘，，但汉族患者反流性咳嗽与反流性哮喘的发生率无显著差异。维族患者反流性咽炎、反流性咳嗽和反流性哮喘的发生率无显著差异；④汉族、维族男性与女性患者三种食管外表现总发生率，反流性咽喉炎、反流性咳嗽和反流性哮喘发生率均无显著差异。汉族男性与女性患者反流性咽喉炎的发生率均高于反流性咳嗽和反流性哮喘，但反流性咳嗽与反流性哮喘的发生率无显著差异。维族男性与女性患者反流性咽喉炎、反流性咳嗽和反流性哮喘的发生率无显著差异；⑤新疆GERD患者三种常见食管外表现的发生之间没有相关性；⑥民族为维族、劳累、吸烟、进食过饱、饮食结构以肉食为主、辛辣饮食和高Gerd Q量表评分是新疆地区GERD患者发生食管外表现的危险因素。结论：新疆GERD患者食管外表现的发生率较高；新疆维族患者食管外表现的发生率与汉族存在显著差异；新疆GERD患者食管外表现的发生之间无相关性；民族为维族、劳累、吸烟、进食过饱、饮食结构以肉食为主、辛辣饮食和高Gerd Q量表评分是新疆GERD患者发生食管外表现的危险因素。
[Abstract]:Objective: to study the incidence and risk factors of extraesophageal manifestations in patients with gastroesophageal reflux disease (GERD) in Xinjiang. Methods: to compare the incidence of three common extraesophageal manifestations (reflux pharyngitis, reflux cough and reflux asthma) in patients with GERD in Xinjiang, and analyze the correlation among the three common extraesophageal manifestations. Objective: to explore the risk factors of extraesophageal manifestations. Results the total incidence of the three common extraesophageal manifestations of GERD in Xinjiang was 47.01, among which the incidence of reflux laryngitis was 27.24%, the reflux cough 15.67 was the second, and the reflux asthma 12.31) was the lowest. 2There was no significant difference between male and female patients with GERD in the total incidence of three common extraesophageal manifestations, reflux laryngitis, reflux cough and reflux asthma. The incidence of reflux pharyngitis was the highest in males, followed by reflux cough and reflux asthma. The incidence of reflux laryngitis in female was higher than that in reflux cough and reflux asthma, but there was no significant difference in the incidence of reflux cough and reflux asthma. The incidence of reflux pharyngitis was lower than that of Han nationality, and the incidence of reflux cough and reflux asthma was higher than that of Han nationality. Reflux pharyngitis is the most common extraesophageal manifestation in Han nationality, and the incidence of reflux cough and reflux asthma is higher than that of reflux cough and reflux asthma, but there is no significant difference between reflux cough and reflux asthma in Han nationality. There was no significant difference in the incidence of reflux pharyngitis, reflux cough and reflux asthma in Uygur patients. There was no significant difference in the incidence of reflux cough and reflux asthma. The incidence of reflux pharyngitis in male and female patients was higher than that in reflux cough and reflux asthma, but there was no significant difference between reflux cough and reflux asthma. There was no significant difference in the incidence of reflux pharyngitis, reflux cough and reflux asthma between male and female Uygur patients. There was no correlation between the occurrence of three common extraesophageal manifestations in Xinjiang GERD patients. Overeating and eating structure were dominated by meat. Spicy diet and high Gerd Q scale were the risk factors of extraesophageal manifestations in GERD patients in Xinjiang. Conclusion: the incidence of extraesophageal manifestations of GERD patients in Xinjiang is higher, the incidence of extraesophageal manifestations of Uygur patients in Xinjiang is significantly different from that of Han nationality, there is no correlation between the occurrence of extraesophageal manifestations of GERD patients in Xinjiang, the nationalities of Uygur nationality are Uygur, tired, smoking, Overeating and eating structure were dominated by meat. Spicy diet and high Gerd Q scale were the risk factors of extraesophageal manifestations in GERD patients in Xinjiang.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R571

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