树脂灌流器与活性碳灌流器治疗高脂血症性胰腺炎的疗效比较

发布时间：2018-05-26 20:38

本文选题：血液灌流 + 树脂灌流器　；参考：《重庆医学》2015年35期

【摘要】：目的对比观察树脂灌流器和活性碳灌流器在高脂血症性胰腺炎(HLP)中的临床应用,以判断其疗效。方法 HLP患者54例,在常规胰腺炎治疗的基础上,采用血液灌流以降低血脂浓度,按使用的灌流器不同分为树脂组和活性碳组,分别使用树脂吸附血液灌流器(HA330)或活性碳灌流器(YTS/200),治疗时间2h。测定血液灌流前、血液灌流治疗结束后12h的血清三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、前降钙素原(PCT)、C-反应蛋白(CRP)值。结果血液灌流治疗前,两组患者血清TG、TC、HDL-C、LDL-C、PCT、CRP等方面比较,差异均无统计学意义(P0.05)。血液灌流治疗结束后12h,两组患者血清TG、TC、LDL-C、PCT、CRP较治疗前均显著降低(P0.05);活性碳组患者血清TG、TC、LDL-C明显低于树脂组患者(P0.01)。结论树脂灌流器与活性碳灌流器均用于治疗HLP,可显著降低患者血脂水平,清除炎性介质。
[Abstract]:Objective to observe the clinical application of resin perfusion apparatus and activated carbon perfusion apparatus in hyperlipidemic pancreatitis. Methods 54 patients with HLP were divided into resin group and activated carbon group by hemoperfusion in order to reduce the concentration of blood lipid on the basis of routine treatment of pancreatitis. Resin adsorbent hemoperfusion apparatus (HA330) or activated carbon perfusion apparatus (YTS / 200) were used for 2 h treatment. The levels of serum triacylglycerol (TGG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), and procalcitonin (PCT) C-reactive protein (CRP) were measured before and 12 hours after hemoperfusion. Results before hemoperfusion treatment, there was no significant difference between the two groups in the serum levels of TGG, TCU, HDL-CU, LDL-CU, PCTU, CRP, and so on (P 0.05). At 12 hours after hemoperfusion treatment, the serum levels of TGN TCU LDL-CnPCTU CRP in both groups were significantly lower than those before treatment, and the serum levels of TGG and TCN LDL-C in the activated carbon group were significantly lower than those in the resin group (P 0.01). Conclusion both resin perfusion and activated carbon perfusion can significantly reduce the level of blood lipid and remove inflammatory mediators in the treatment of HLP.
【作者单位】：南昌大学附属赣州市人民医院重症医学科;
【分类号】：R576;R589.2

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