放大电子色素内镜下急慢性胃炎特点及与幽门螺杆菌感染相关性分析

发布时间：2018-05-31 10:04

本文选题：H.pylori.感染 + 放大电子色素内镜　；参考：《中国内镜杂志》2015年02期

【摘要】：目的分析放大电子色素内镜下胃窦炎症的微形态特征及其与H.pylori.感染的关系,评价其用于靶向活检的可行性。方法消化内镜室行放大窄带成像内镜检查的连续的患者为研究对象,将内镜下黏膜表面形态分5型,以快速尿素酶试验并病理组织学特殊染色查H.pylori.结果为标准,比较黏膜表面形态和H.pylori.感染的关系。结果最终共有65例患者的159个部位与病理组织学及H.pylori.检测结果进行分析。正常胃窦黏膜以A型(70.8%)多见,慢性炎症和急性炎症以B型形态(82.1%)和C型形态(82.8%)为主。肠上皮化生主要表现为D型和E型形态(77.5%)。H.pylori.感染阳性部位共58个(36.5%),以B型和C型形态为多,分别占B型和C型部位的60.0%和60.7%。B型和C型形态预测H.pylori.感染的敏感度为70.1%(95%CI[58.3,81.9]),特异度为73.3%[64.7,81.9],准确度为72.3%[65.3,79.3]。结论胃窦黏膜H.pylori.感染在放大电子色素内镜下微血管和腺管形态有其特征性,预测H.pylori.感染有较高的诊断价值,可提高靶向活检的阳性率。
[Abstract]:Objective to analyze the micromorphologic features of sinusitis under magnified electronic pigment endoscopy and its relationship with H. pylori. The relationship between infection and its feasibility for targeted biopsy was evaluated. Methods A series of patients with endoscopically enlarged narrow-band imaging were studied. The mucosal surface morphology was divided into 5 types. Rapid urease test and histopathological special staining were used to detect H. pylorius. The results showed that the mucosal surface morphology was compared with that of H. pylori. The relationship between infection. Results A total of 159 sites, histopathology and H. pylorius were found in 65 patients. The test results were analyzed. The normal antral mucosa was mainly type A (70.8), chronic inflammation and acute inflammation were mainly type B (82.1) and type C (82.8). The intestinal metaplasia was mainly characterized by D and E forms. There were 58 positive sites, most of which were B and C, which accounted for 60.0% and 60.7% of B and C, respectively, to predict H. pylorius. The sensitivity, specificity and accuracy of 70.1%(95%CI were 73.3% and 72.3%, respectively. Conclusion H.pylori. Microvascular and glandular tubules are characterized by magnified electron pigment endoscopy, and H.pylorius is predicted. Infection has high diagnostic value and can improve the positive rate of targeted biopsy.
【作者单位】：首都医科大学附属北京世纪坛医院消化科;
【分类号】：R573.3

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