炎症性肠病患者服药依从性及其影响因素研究

发布时间：2018-06-04 17:15

本文选题：炎症性肠病 + 服药依从性　；参考：《中国全科医学》2017年32期

【摘要】：目的调查炎症性肠病(IBD)患者服药依从性现状及其影响因素。方法选取2014年11月—2015年11月在江苏省人民医院和常州市中医院消化科就诊的IBD患者。采用改良的Morisky量表对IBD患者服药依从性进行评价;采用一般情况调查问卷、中文版克罗恩病与溃疡性结肠炎知识问卷(CCKNOW)、Zung焦虑/抑郁自评量表(SAS/SDS)和社会支持评定量表进行调查,纳入可能对IBD患者服药依从性产生影响的因素,进行单因素分析和多元逐步线性回归分析。结果共调查126例IBD患者,有效问卷118份,有效回收率为93.6%。其中溃疡性结肠炎(UC)患者92例,克罗恩病(CD)患者26例。IBD患者服药依从性评分为(11.3±3.7)分,其中UC患者为(10.9±3.4)分,CD患者为(12.8±4.1)分,两者比较,差异有统计学意义(t=-2.365,P=0.020)。单因素分析结果显示,不同职业、文化程度、油腻食物、饮食结构、疾病类型、药物不良反应者服药依从性评分比较,差异均有统计学意义(P0.05);年龄、CCKNOW评分、社会支持评分与服药依从性评分呈负相关(P0.05);服药总数、SDS评分与服药依从性评分呈正相关(P0.05)。多元线性回归分析结果显示,文化程度、年龄、服药总数、CCKNOW评分、社会支持评分是服药依从性评分的影响因素(P0.05)。结论 IBD患者服药依从性较差,在今后的临床工作中要重视年龄、文化程度对IBD患者服药依从性的预警作用,同时要提高患者社会支持程度和知识宣教力度,简化用药方案,提高IBD患者服药依从性。
[Abstract]:Objective to investigate the status and influencing factors of drug compliance in patients with inflammatory bowel disease (IBD). Methods IBD patients were selected from November 2014 to November 2015 in the Digestive Department of Jiangsu Provincial people's Hospital and Changzhou traditional Chinese Medicine Hospital. The modified Morisky scale was used to evaluate the compliance of IBD patients with medication, and the Chinese version of the knowledge questionnaire on Crohn's disease and ulcerative colitis (CCKNOWN Zung anxiety / depression self-rating scale) and the social support rating scale were used to investigate the compliance of the patients with the drug taking medicine, and the Chinese version of the questionnaire on knowledge of Crohn's disease and ulcerative colitis. Single factor analysis and multiple stepwise linear regression analysis were carried out. Results A total of 126 patients with IBD were investigated, 118 effective questionnaires were obtained, and the effective recovery rate was 93. 6%. There were 92 patients with ulcerative colitis and 26 patients with Crohn's disease. The compliance score of IBD was 11.3 卤3.7, and the score of UC was 10.9 卤3.4 and the score of CD was 12.8 卤4.1. The difference was statistically significant. Univariate analysis showed that there were significant differences among different occupations, education levels, fatty foods, dietary structure, disease types, drug compliance scores of patients with adverse drug reactions (P 0.05), age and CCKNOW scores. There was a negative correlation between social support score and drug compliance score (P 0.05), and a positive correlation between SDS score and drug compliance score (P 0.05). The results of multiple linear regression analysis showed that education level, age, total dose of medication and CCKNOW score, social support score were the influencing factors of drug compliance score (P 0.05). Conclusion the drug compliance of IBD patients is poor. In the future clinical work, we should pay attention to the early warning effect of age and education level on the drug taking compliance of IBD patients, at the same time, we should improve the degree of social support and knowledge propaganda of patients, and simplify the drug use plan. To improve the compliance of patients with IBD.
【作者单位】：南京中医药大学;江苏省人民医院;江苏省常州市中医院;
【基金】：国家自然科学基金面上资助项目(71573140) 江苏省优势学科二期项目南京中医药大学护理学一级学科指令性课题(YSHL2016-007)
【分类号】：R574

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