缺氧性肝炎的临床特征及预后因素分析

发布时间：2018-06-10 10:47

本文选题：缺氧性肝炎 + 诊断　；参考：《医学与哲学(B)》2017年03期

【摘要】：分析缺氧性肝炎患者的临床特征及影响预后的危险因素。收集缺氧性肝炎患者41例,其中死亡18例(死亡组),生存23例(存活组),病死率为43.9%,分析患者临床资料。结果显示:缺氧性肝炎患者平均年龄(74.7±12.5)岁,以70岁~89岁患者居多(占73.2%),并发于感染性休克者占70.7%;死亡组患者中合并冠心病及糖尿病的百分数均明显高于生存组,差异有统计学意义(P0.05);死亡组患者AST、LDH、INR、Cre、Bun、乳酸水平分别明显高于生存组,差异有统计学意义(P0.05),死亡组患者的pH、HCO_3~-水平分别明显低于生存组,差异有统计学意义(P0.05),死亡组患者中合并酸中毒者的百分数明显高于生存组,差异有统计学意义(P0.05);合并冠心病、糖尿病是影响缺氧性肝炎预后的危险因素(OR值分别为6.44、4.59,P0.05)。可见缺氧性肝炎多见于老年患者,常并发于感染性休克,病死率较高,冠心病、糖尿病是影响其预后的危险因素。
[Abstract]:To analyze the clinical characteristics and prognostic factors of patients with hypoxic hepatitis. Among 41 patients with hypoxic hepatitis, 18 died (death group) and 23 survived (survival group, mortality rate was 43.9). The clinical data of the patients were analyzed. The results showed that the average age of patients with hypoxic hepatitis was 74.7 卤12.5 years old, the majority of patients were 70 years old and 89 years old (73.2%, 70.7% of patients complicated with septic shock), the percentage of patients with coronary heart disease and diabetes mellitus in the death group was significantly higher than that in the survival group. The level of lactic acid in the dead group was significantly higher than that in the survival group, and the difference was statistically significant (P 0.05). The pH value of HCO3 in the dead group was significantly lower than that in the survival group. The percentage of patients with acidosis in the death group was significantly higher than that in the survival group, the difference was statistically significant (P 0.05), and the OR value of diabetes mellitus was 6.44.59% and 6.44.59% respectively with coronary heart disease. It can be seen that hypoxic hepatitis is more common in elderly patients, often complicated with septic shock, with high mortality. Coronary heart disease and diabetes mellitus are the risk factors affecting the prognosis.
【作者单位】：大连市中心医院消化内科;大连市中心医院病理科;大连医科大学附属第一医院消化内科;
【基金】：2015年辽宁省自然科学基金资助项目(2015020324)
【分类号】：R575.1

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