健脾利水方联合输血治疗肝硬化腹水临床疗效观察及对肝功能和肾功能的影响

发布时间：2018-06-14 08:05

本文选题：健脾利水方 + 输血　；参考：《中华中医药学刊》2015年08期

【摘要】：目的:探讨健脾利水方联合输血治疗肝硬化腹水临床疗效观察及对患者肝功能和肾功能的影响。方法:根据随机数字表法将本组纳入的108例肝硬化腹水患者随机分为治疗组(n=54)和对照组(n=54)。两组患者均给予常规对症治疗。治疗组采用健脾利水方联合输血治疗,对照组采用西药治疗。两组均以4周为1个疗程,共治疗2个疗程。对比分析两组患者治疗2个疗程后疗效,治疗前后肝功能、肾功能水平及治疗期间不良反应发生情况。结果:治疗组治疗2个疗程后总有效率(87.04%)显著高于对照组(68.52%),且具有统计学差异(P0.05);治疗组ALB治疗后显著高于对照组,而ALT、AST治疗后显著低于对照组,且有统计学差异(P0.05);治疗组Cr、BUN水平治疗后显著低于对照组,且具有统计学差异(P0.05);治疗期间均未发生明显不良反应。结论:健脾利水方联合输血治疗肝硬化腹水临床疗效显著,可明显改善患者肝、肾功能,且无明显不良反应,临床应用安全可靠,值得进一步推广应用。
[Abstract]:Objective: to investigate the effect of Jianpi Lishui recipe combined with blood transfusion on liver function and renal function in patients with cirrhosis and ascites. Methods: 108 cirrhotic ascites patients were randomly divided into treatment group (n = 108) and control group (n = 54). Both groups were given routine symptomatic treatment. The treatment group was treated with Jianpi Lishui decoction combined with blood transfusion, while the control group was treated with western medicine. The two groups were treated with 4 weeks as a course of treatment, a total of 2 courses of treatment. The curative effect, liver function, renal function and adverse reaction during treatment were compared between the two groups. Results: the total effective rate of the treatment group was significantly higher than that of the control group after two courses of treatment (P 0.05), and the ALB of the treatment group was significantly higher than that of the control group, while the alt AST was significantly lower than that of the control group. The level of Cr bun in the treatment group was significantly lower than that in the control group (P 0.05) and there was no significant adverse reaction during the treatment. Conclusion: the combination of Jianpi Lishui recipe and blood transfusion in the treatment of ascites due to liver cirrhosis is effective in the treatment of ascites due to cirrhosis. It can obviously improve the liver and renal function of the patients and has no obvious adverse reactions. It is safe and reliable in clinical application and is worthy of further popularization and application.
【作者单位】：象山县第一人民医院;
【分类号】：R575.2

【参考文献】