血清白蛋白、前白蛋白和转铁蛋白在评价慢性肝衰竭患者营养支持中的应用

发布时间：2018-06-19 14:59

本文选题：前白蛋白 + 转铁蛋白　；参考：《实用医学杂志》2017年04期

【摘要】：目的:通过监测白蛋白、前白蛋白和转铁蛋白的变化情况,观察其在快速评价慢性肝衰竭营养现况和预后中的作用。方法:收集慢性肝衰竭患者的入院时基线血清营养指标,并检测给与营养支持治疗7、14、21 d后,血清白蛋白、前白蛋白和转铁蛋白的变化情况。结果:基线血清白蛋白和前白蛋白水平较低的患者,其住院时间相对较长且预后较差,差异具有统计学意义(P0.05)。患者接受营养支持后,其前白蛋白和转铁蛋白水平显著升高(P0.05),组间比较结果提示:营养支持7 d后,前白蛋白和转铁蛋白较基线显著升高(P0.05)。结论:基线血清白蛋白和前白蛋白水平与患者住院时间和预后相关,前白蛋白和转铁蛋白可作为评估患者营养状况恢复的早期敏感指标。
[Abstract]:Aim: to investigate the role of albumin, prealbumin and transferrin in rapid assessment of nutritional status and prognosis of chronic liver failure (CHF) by monitoring the changes of albumin, prealbumin and transferrin. Methods: the baseline serum nutritional parameters of patients with chronic liver failure were collected and the changes of serum albumin, prealbumin and transferrin were detected 21 days after treatment with nutritional support. Results: the patients with lower baseline serum albumin and prealbumin had a relatively long hospital stay and poor prognosis, and the difference was statistically significant (P 0.05). After nutritional support, the levels of prealbumin and transferrin increased significantly (P 0.05). The results showed that after 7 days of nutrition support, prealbumin and transferrin increased significantly compared with baseline. Conclusion: baseline serum albumin and prealbumin levels are related to the duration of hospitalization and prognosis. Prealbumin and transferrin can be used as an early sensitive index to evaluate the recovery of nutritional status of patients.
【作者单位】：郑州大学第二附属医院;河南省人民医院感染科;
【基金】：2014河南省科技厅基础与前沿技术项目(编号:142300410372)
【分类号】：R575.3

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