代谢综合征与非酒精性脂肪肝的相关性分析

发布时间：2018-07-03 02:39

本文选题：非酒精性脂肪肝 + 代谢综合征　；参考：《现代预防医学》2015年22期

【摘要】：目的通过流行病学调查,分析非酒精性脂肪性肝病(NAFLD)的相关危险因素,以探讨NAFLD与代谢综合征(MS)的相关性。方法 873人依据体检情况分为NAFLD组和非NAFLD组及MS组和非MS组,分析体重指数(BMI)、血压、血脂、血糖(FBG)等因素与NAFLD的相关性。结果 (1)NAFLD患病率41.123%,男性患病率高于女性(χ2=21.804,P0.001)。MS患病率15.693%,MS组NAFLD患病率高于非MS组(χ2=99.171,P0.001)。(2)NAFLD组BMI、FBG、收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白(LDL-C)、谷丙转氨酶(ALT)、尿酸(UA)值均高于非NAFLD组(P0.001),谷草转氨酶(AST)值高于非NAFLD组(t=3.242,P=0.001),HDL-C值低于非NAFLD组(t=3.510,P0.001);超重和(或)肥胖、高血糖、高血压、高TG、低HDL-C、高尿酸血症、MS阳性率均高于非NAFLD组(P0.001),肝功能异常阳性率高于非NAFLD组(t=10.119,P=0.002)。(3)NAFLD患病率随着MS诊断标准中诊断项目的增多呈上升趋势(χ2=239.918,P0.001)。结论 MS与NAFLD密切相关,并相互影响。
[Abstract]:Objective to investigate the correlation between NAFLD and metabolic syndrome (MS) by analyzing the risk factors of nonalcoholic fatty liver disease (NAFLD). Methods 873 patients were divided into NAFLD group, non-NAFLD group, MS group and non-MS group according to physical examination. The correlation between body mass index (BMI), blood pressure, blood lipid, blood glucose (FBG) and NAFLD was analyzed. Results (1) the prevalence rate of NAFLD in males was higher than that in females (蠂 2: 21.804 / P0.001). The prevalence rate of MS was 15.693C. The prevalence rate of NAFLD in MS group was higher than that in non-MS group (蠂 2 99.171 P0.001). (2). Systolic blood pressure (SBP), diastolic blood pressure (DBP), triglyceride (TG), cholesterol (TC), low density lipoprotein cholesterol (LDL-C), alanine aminotransferase (alt), uric acid (UA) were all higher. The values of glutamic oxaloacetic transaminase (AST) were higher than those of non-NAFLD group (tnafLD) (t = 3.242) and HDL-C were lower than those of non-NAFLD group (t = 3.510p 0.001), and were overweight and / or obese, and the level of HDL-C was higher than that of non-NAFLD group (P 0.001). The positive rate of MS in hyperglycemia, hypertension, hyperglycemia, low HDL-Cand hyperuricemia group was higher than that in non-NAFLD group (P0.001), and the positive rate of abnormal liver function was higher than that in non-NAFLD group (tnd10.119P0.0002). (3). The prevalence rate of NAFLD increased with the increase of diagnostic items in MS diagnostic criteria (蠂 2239.918P 0.001). Conclusion MS is closely related to NAFLD and interacts with each other.
【作者单位】：山东中医药大学;山东中医药大学第一附属医院;
【分类号】：R589;R575.5

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