内镜下治疗慢性胰腺炎的临床疗效及对患者腹痛症状改善程度的研究

发布时间：2018-07-08 15:54

本文选题：内镜 + 慢性胰腺炎　；参考：《中国内镜杂志》2017年10期

【摘要】：目的对内镜下治疗慢性胰腺炎(CP)的临床疗效进行观察,并分析患者腹痛症状的改善程度,为临床提供参考依据。方法选择该院2011年7月-2013年6月经内镜下治疗的CP患者81例,观察其疗效、并发症和腹痛情况。结果 81例患者手术均获成功,无死亡病例。术后1周疼痛平均分为(2.29±0.14)分,低于术前(7.13±0.27)分,差异有统计学意义(P0.05)。术后1周无痛、轻度疼痛和中度疼痛分别为46.91%(38/81)、35.80%(29/81)和13.58%(11/81),均高于术前(P0.05)。术后1周重度疼痛为3.70%(3/81),低于术前56.79%(46/81)(P0.05)。术后1周脂肪泻和营养不良分别0.00%(0/81)和7.41%(6/81),均低于术前25.93%(21/81)和37.04%(30/81),差异有统计学意义(P0.05)。术后1周血清淀粉酶平均浓度为(74.18±2.75)u/L,低于术前(182.45±8.32)u/L,差异有统计学意义(P0.05)。结论内镜下治疗CP并发症较少,疗效可靠,具有微创、可重复等优点,可有效治疗慢性胰腺炎患者并能够有效缓解其腹痛。
[Abstract]:Objective to observe the clinical effect of endoscopic treatment of chronic pancreatitis (CP) and analyze the improvement of abdominal pain symptoms. Methods Eighty-one patients with CP treated by endoscopy from July 2011 to June 2013 were selected and the curative effect, complications and abdominal pain were observed. Results all the 81 patients were successfully operated, and there were no death cases. The average score of pain was (2.29 卤0.14), lower than that before operation (7.13 卤0.27), the difference was statistically significant (P0.05). The painless, mild and moderate pain were 46.91% (38 / 81) or 35.80% (29 / 81) and 13.58% (11 / 81), respectively, which were higher than those before operation (P0.05). Severe pain was 3.70% (3 / 81) 1 week after operation, which was lower than that before operation 56.79% (46 / 81) (P0.05). 1 week after operation, fatty diarrhea and malnutrition were 0.00% (0 / 81) and 7.41% (6 / 81), respectively, which were significantly lower than those before operation (25.93% (21 / 81) and 37.04% (30 / 81), P 0.05). The average serum amylase concentration was (74.18 卤2.75) U / L at 1 week postoperatively, which was lower than that before operation (182.45 卤8.32) u / L, the difference was statistically significant (P0.05). Conclusion Endoscopic treatment of CP has the advantages of less complications, reliable curative effect, minimally invasive and repeatable, and can effectively treat patients with chronic pancreatitis and relieve abdominal pain.
【作者单位】：浙江省嘉兴市第二医院消化内科;浙江省嘉兴市第二医院肝胆外科;
【分类号】：R576

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