2014年安徽省1-29岁人群乙型病毒性肝炎血清流行病学调查

发布时间：2018-07-10 14:58

本文选题：乙型 + 病毒性肝炎　；参考：《现代预防医学》2017年09期

【摘要】：目的为进一步加强乙肝防控工作,详细掌握全省现阶段人群乙肝流行状况,评价乙肝疫苗引入以来乙肝防控效果。方法采用分层整群随机抽样方法从全省设立的6个乙肝监测点按照城市和农村分层选取1 587名年龄1-29岁的人群样本,采集静脉血,并采用国产酶联免疫吸附试验(Enzyme-Linked Immunosorbent Assay,ELISA)试剂进行检测。结果本次调查1 587名对象,男女比例1∶1.01。人群HBV感染率10.78%。15岁以下年龄组HBsAg均为阴性,HBsAb阳性率1岁组最高,9-10岁组最低,25岁以上人群HBV感染率及HBsAg、HBcAb阳性率均较高。城市人群HBcAb阳性率、HBV感染率高于农村(P0.001);HBsAg阳性率、HBcAb阳性率和HBV感染率在医护人群、服务人群和其他人群中的差异有统计学意义(P0.001);HBsAg阳性率、HBsAb阳性率、HBcAb阳性率和HBV感染率与免疫史之间的差异均有统计学意义(P0.001)。本次调查结果与2006年相比,人群乙肝感染率有较大幅度下降。结论安徽省将乙肝疫苗纳入免疫规划以来,不断提高适龄人群乙肝疫苗接种率和及时率,目标人群乙肝防控工作取得了显著的成绩。
[Abstract]:Objective to further strengthen the prevention and control of hepatitis B, to understand the epidemic situation of hepatitis B in the whole province at present in detail, and to evaluate the effect of hepatitis B prevention and control since the introduction of hepatitis B vaccine. Methods the stratified cluster random sampling method was used to collect venous blood from 6 hepatitis B surveillance sites in the province according to urban and rural stratified population samples aged 1-29 years. Enzyme-Linked Immunosorbent Assayosorbent Elisa (Elisa) was used to detect the results. Results the ratio of male to female was 1: 1.01. The positive rate of HBsAg was negative in the age group of 10. 78 and below 15 years old. The highest positive rate of HBsAg in the age group of 9 to 10 years old and the highest rate of HBV infection rate and the positive rate of HBcAb of HBsAg in the group of above 25 years old were higher than those in the age group of 9-10 years old. The positive rate of HBcAb in urban population was higher than that in rural area (P0.001). There were significant differences in HBsAg positive rate and HBcAb positive rate between service population and other population (P0.001). There was significant difference between HBcAb positive rate and HBV infection rate and immunization history (P0.001). The results of this survey compared with 2006, the population hepatitis B infection rate has a large decline. Conclusion since the introduction of hepatitis B vaccine into the immunization program in Anhui Province, the coverage rate and timely rate of hepatitis B vaccine have been continuously increased, and significant achievements have been made in the prevention and control of hepatitis B among the target population.
【作者单位】：安徽省疾病预防控制中心;
【分类号】：R512.62

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