不同服药速度对聚乙二醇电解质溶液肠道准备的效果评价

发布时间：2018-07-28 17:06

【摘要】：目的评价复方聚乙二醇电解质溶液(PEG-ES)不同服药速度作为肠道准备方案的清洁效果和耐受性。方法连续纳入97例拟行肠镜检查患者,随机分为A组(试验组)和B组(对照组)。A组:2 000 ml PEG-ES,每10~20 min内快速服用1 000 ml,1 h内服完。B组:2 000 ml PEG-ES,每10 min服用250 ml,2 h内服完。观察指标:总服药时间、服药后第一次排便时间、总排便次数、Boston肠道准备量表(BBPS)评分和不良反应发生情况。结果 A组与B组间性别、年龄和盲肠插管率差异无统计学意义(P0.05)。A组服药时间、首次排便时间明显短于B组,而总排便次数明显多于B组(P0.05)。两组患者均未出现呕吐及腹痛等不良发应,但A组恶心及腹胀发生率高于B组(P0.05),但发生率均小于10.00%。A组患者肠道准备接受率低于B组,但均超过90.00%,A组再次肠镜检查接受率明显高于B组(P0.05)。A组右半结肠、横结肠评分及总分明显高于B组(P0.05),但左半结肠评分差异无统计学意义(P0.05)。结论两种方案均能满足常规结肠镜检查的要求,1 h内快速服PEG-ES的结肠镜检查肠道准备方案能获得更满意的肠道清洁效果。
[Abstract]:Objective to evaluate the efficacy and tolerance of different dosage of polyethylene glycol electrolyte solution (PEG-ES) as an enteric preparation scheme. Methods 97 patients were randomly divided into group A (test group) and group B (control group).A: 2000 ml PEG-ES, 1000 ml in every 10~20 min, 1 h in.B group: 2000 m L PEG-ES, taking 250 ml and 2 h for every 10 min. Observation indexes: total taking time, the first defecation time, total defecation time, Boston bowel preparation scale (BBPS) score and adverse reaction. Results there was no significant difference in sex, age and cecum intubation rate between group A and B group (P0.05).A group taking time, first defecation The time of the total defecation was significantly shorter than that of the group B (P0.05). No vomiting and abdominal pain were found in the two groups, but the incidence of nausea and abdominal distention in the group A was higher than that of the B group (P0.05), but the incidence of intestinal preparation was lower than that of the group of 10.00%.A (P0.05), but the rate of intestinal preparation was lower than that of the group B, but it was more than that of the group B, but all of the patients were more than those in the group of 10.00%.A, but the rate of acceptance of the colonoscopy in the group A was significantly higher. The score and total score of the transverse colon were significantly higher in the right semicolon in group B (P0.05).A than in group B (P0.05), but there was no significant difference between the left semicolon score (P0.05). Conclusion the two schemes could meet the requirements of routine colonoscopy, and the fast PEG-ES colonoscopy for intestinal tract preparation within 1 h could obtain a more satisfactory intestinal cleaning effect.
【作者单位】：安徽医科大学第二附属医院消化内科;
【基金】：安徽省自然科学基金(No:1408085MH178)
【分类号】：R57

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