早期经口进食在重症急性胰腺炎中的研究进展
发布时间:2018-08-16 12:42
【摘要】:重症急性胰腺炎(severe acute pancreatitis,SAP)是临床上常见的一种急危重症,目前临床中普遍认为高能量消耗、高分解代谢、严重的负氮平衡导致的营养不良对SAP患者的预后极其不利。因此营养支持成为治疗SAP最重要的手段之一,对SAP的转归有重要影响。研究证实肠内营养(enteral nutrition,EN)与全肠外营养(total parenteral nutrition,TPN)相比可降低重症急性胰腺炎患者的病死率,减少感染并发症及器官衰竭的发生率。其中,EN中的经口进食不仅能减轻患者导管输入营养的痛苦,减少操作并发症,同时可能对胰腺存在保护作用,具有较好的应用前景和临床实用价值。本文就早期经口进食进行肠内营养在治疗SAP的安全性及有效性做一综述。
[Abstract]:Severe acute pancreatitis (severe acute) is a common acute and critical disease. At present, it is generally considered that high energy consumption, high catabolism and severe negative nitrogen balance caused by malnutrition are extremely unfavorable to the prognosis of SAP patients. Therefore, nutritional support has become one of the most important methods in the treatment of SAP and has an important effect on the outcome of SAP. It has been demonstrated that enteral nutrition (en) can reduce the mortality rate and the incidence of infection and organ failure in patients with severe acute pancreatitis compared with total parenteral nutrition (total parenteral nutation en). The oral feeding in en can not only alleviate the pain of catheter feeding, reduce the complications of operation, but also protect the pancreas, which has a good application prospect and clinical value. This article reviews the safety and efficacy of early oral enteral nutrition in the treatment of SAP.
【学位授予单位】:重庆医科大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R576
本文编号:2186015
[Abstract]:Severe acute pancreatitis (severe acute) is a common acute and critical disease. At present, it is generally considered that high energy consumption, high catabolism and severe negative nitrogen balance caused by malnutrition are extremely unfavorable to the prognosis of SAP patients. Therefore, nutritional support has become one of the most important methods in the treatment of SAP and has an important effect on the outcome of SAP. It has been demonstrated that enteral nutrition (en) can reduce the mortality rate and the incidence of infection and organ failure in patients with severe acute pancreatitis compared with total parenteral nutrition (total parenteral nutation en). The oral feeding in en can not only alleviate the pain of catheter feeding, reduce the complications of operation, but also protect the pancreas, which has a good application prospect and clinical value. This article reviews the safety and efficacy of early oral enteral nutrition in the treatment of SAP.
【学位授予单位】:重庆医科大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R576
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