改良二甲硅油散使用方法在结直肠癌筛查中的应用

发布时间：2018-10-21 12:28

【摘要】：背景目前应用于结直肠癌筛查的结肠镜检查中,常规二甲硅油散使用方法存在资源浪费的情况。目的找寻一种更经济有效的二甲硅油散使用方法。方法选取2015年1月—2016年6月在重庆市第五人民医院行结肠镜检查的受检者275例为研究对象。采用随机双盲法将受检者分为试验组(136例)和对照组(139例)。肠道准备时,试验组仅口服聚乙二醇4000散,对照组则口服聚乙二醇4000散后,继续予以二甲硅油散;结肠镜检查进镜时,如发现肠道泡沫,两组均予以二甲硅油散兑水冲洗吸引。记录两组进镜时肠道泡沫分级、退镜时肠道泡沫情况、结肠镜检查时间、二甲硅油散使用数量。结果根据剔除标准剔除了7例患者,最终共纳入268例受检者,其中试验组132例、对照组136例。试验组进镜时肠道泡沫分级大于对照组,二甲硅油散使用数量小于对照组,差异有统计学意义(P0.05);两组结肠镜检查时间比较,差异无统计学意义(P0.05)。两组退镜时肠道泡沫情况均达标。结论改良二甲硅油散使用方法 (仅在进镜时使用二甲硅油散兑水冲洗)既能够达到结直肠癌筛查中结肠镜检查全结肠无泡沫的要求,又不会延长结肠镜检查时间,二甲硅油散使用量也明显减少,简单易行,可以在今后的结直肠癌筛查中继续使用。
[Abstract]:Background in colonoscopy of colorectal cancer screening, there is a waste of resources in conventional dimethylsiloxane powder. Objective to find a more economical and effective method for the use of dimethylsiloxane powder. Methods 275 patients who underwent colonoscopy in the Fifth people's Hospital of Chongqing from January 2015 to June 2016 were selected as subjects. The subjects were randomly divided into two groups: experimental group (136 cases) and control group (139 cases). During intestinal preparation, the test group only took polyethylene glycol 4000 powder, while the control group received dimethylsiloxane powder after taking polyethylene glycol 4000 powder, and both groups were given dimethylsiloxane oil powder after colonoscopy examination, if the intestinal foam was found, both groups were treated with dimethylsiloxane oil powder and water. The grades of intestinal foam in the two groups, the foaming condition of the intestine at the time of endoscopy, the time of colonoscopy and the amount of dimethylsiloxane powder were recorded. Results according to the exclusion criteria, 7 patients were excluded, and 268 patients were included in the study group (132 cases) and the control group (136 cases). The intestinal foam grade in the experimental group was larger than that in the control group, and the amount of dimethylsiloxane powder was smaller than that in the control group (P0.05); there was no significant difference in colonoscopy time between the two groups (P0.05). The foaming condition of intestinal tract in both groups was up to the standard at the time of devitalization. Conclusion the modified method of using dimethylsiloxane oil powder (only using dimethylsiloxane oil powder and water for washing during endoscopy) can not only meet the requirements of colonoscopy without foaming in colorectal cancer screening, but also do not prolong the time of colonoscopy. The use of dimethylsiloxane powder is also significantly reduced, easy to use, can be used in colorectal cancer screening in the future.
【作者单位】：重庆市第五人民医院消化内镜中心;
【分类号】：R574.62;R735.3

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