不同发病年龄溃疡性结肠炎273例临床对比分析

发布时间：2018-10-23 08:21

【摘要】：目的:回顾性分析溃疡性结肠炎病人的一般情况、病变范围、临床特点、病变严重程度,旨在比较近5年新疆地区不同发病年龄溃疡性结肠炎的临床特点和预后,为今后临床研究提供理论依据。方法:收集2012年1月至2016年3月新疆医科大学第一附属医院符合2012年中华医学会消化病学分会(广州会议)制定的《炎症性肠病诊断与治疗的共识意见》诊断标准的溃疡性结肠炎患者273例。从溃疡性结肠炎的一般临床特征、病程、病变范围、治疗用药等进行回顾性分析,依据其发病年龄将其分为年轻发病组(young-onset,YO,yr30)和成人发病组(adult-onset,AO,yr≥30)。采用统计软件SPSS17.0进行统计学分析,计数资料以百分率描述,计量资料采用均数±标准差表示,采用方差分析、卡方检验对结果进行统计学分析,当P0.05时有统计学意义。结果:本研究YO组共53例(平均确诊年龄:23.2±4.8岁),AO组共220例(平均确诊年龄:48.3±11.8岁);YO组较AO组更容易发生广泛性结肠炎或全结肠炎(E3 22/43(51.2%)VS E3 58/184(31.5%))。结论:YO组的临床表现比AO组更加严重。YO组需要更加精心的护理和针对性的治疗方法。
[Abstract]:Objective: to analyze retrospectively the general situation, range of pathological changes, clinical features and severity of ulcerative colitis in Xinjiang in order to compare the clinical features and prognosis of ulcerative colitis at different ages in Xinjiang in recent 5 years. To provide theoretical basis for future clinical research. Methods: from January 2012 to March 2016, the first affiliated Hospital of Xinjiang Medical University was collected according to the diagnostic criteria for diagnosis and treatment of inflammatory bowel disease, which was formulated by the Chinese Society of Digestive Diseases (Guangzhou Conference) of the Chinese Medical Association in 2012. There were 273 cases of ulcerative colitis. According to the general clinical features, course of disease, range of pathological changes and drug therapy of ulcerative colitis, the patients were divided into young onset group (young-onset,YO,yr30) and adult group (adult-onset,AO,yr 鈮，

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