腧穴热敏化悬灸辅助治疗腹泻型肠易激综合征效果观察

发布时间：2018-11-24 13:25

【摘要】：目的观察腧穴热敏化悬灸辅助治疗腹泻型肠易激综合征(IBS-D)的效果,及其对患者血清脑肠肽P物质(SP)、血管活性肠肽(VIP)、乙酰胆碱(Ach)、生长抑素(SS)水平的影响。方法将80例IBS-D患者随机分为观察组和对照组各40例,两组均口服马来酸曲美布汀胶囊,观察组另予腧穴热敏化悬灸辅助治疗,6 d为1个疗程,共治疗4个疗程。治疗前后行临床症状评分判断临床疗效,取静脉血检测血清SP、VIP、Ach、SS,评价并记录患者治疗总有效率。结果观察组总有效率85.0%,高于对照组的67.5%(P0.05)。两组治疗后血清SP、VIP、Ach水平较治疗前降低(P均㩳0.05),且观察组低于对照组(P均㩳0.05);两组血清SS水平治疗前后比较差异无统计学意义。结论采用腧穴热敏化悬灸辅助治疗IBS-D患者,可通过降低血清SP、VIP、Ach水平提高临床疗效。
[Abstract]:Objective to observe the effect of heat sensitized moxibustion at acupoints on diarrhea irritable bowel syndrome (IBS-D) and its effect on serum (SP), vasoactive intestinal peptide (VIP), acetylcholine (Ach),. Effect of somatostatin (SS) level. Methods Eighty patients with IBS-D were randomly divided into observation group (n = 40) and control group (n = 40). Trimebutine maleate capsules were given orally in both groups. The clinical effect was evaluated by clinical symptom score before and after treatment. The total effective rate of treatment was evaluated and recorded by taking venous blood to detect serum SP,VIP,Ach,SS,. Results the total effective rate of the observation group was 85.0%, which was higher than that of the control group (67.5%) (P0.05). After treatment, the serum SP,VIP,Ach level in the two groups was lower than that in the control group (P < 0. 05), and the level of serum SS in the observation group was lower than that in the control group (P? 0. 05), and there was no significant difference between the two groups before and after treatment. Conclusion Thermosensitization of acupoint suspension moxibustion can improve the clinical efficacy of IBS-D patients by decreasing the level of serum SP,VIP,Ach.
【作者单位】：广西中医药大学附属瑞康医院;
【基金】：广西壮族自治区卫生和计划生育委员会研项目(Z2014139);广西壮族自治区卫生和计划生育委员会中医药科技专项(GZLC16-21) 广西中医药大学自然科学基金项目(2015LX031)
【分类号】：R574.4

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