幽门螺杆菌感染与慢性胃炎患者胃黏膜病理变化的相关性分析

发布时间：2018-11-25 08:35

【摘要】：目的分析探讨幽门螺杆菌感染与慢性胃炎患者胃黏膜病理变化的相关性,为临床治疗提供参考依据。方法选择2013年5月-2015年4月在医院接受门诊或者住院治疗的慢性胃炎患者70例为研究对象,根据胃镜检查情况分为试验组和对照组,对照组16例为非慢性萎缩性胃炎患者,试验组54例为慢性萎缩性胃炎,比较两组患者阳性率,并分析幽门螺杆菌感染与慢性胃炎病理变化的相关性,数据采用SPSS 16.0软件进行统计分析。结果试验组阳性率为72.2%,明显高于对照组的37.5%,两组比较,差异有统计学意义(P0.05);随着幽门螺杆菌感染阳性率的升高,慢性胃炎的炎症程度、肠化程度及活动性逐渐提升。结论幽门螺杆菌感染与慢性胃炎患者胃黏膜的病理变化有密切关系,可反映慢性胃炎炎症程度及萎缩程度。
[Abstract]:Objective to investigate the relationship between Helicobacter pylori infection and gastric mucosal pathological changes in patients with chronic gastritis. Methods from May 2013 to April 2015, 70 patients with chronic gastritis who received outpatient or inpatient treatment in hospital were divided into experimental group and control group according to gastroscopy. 16 cases in control group were non-chronic atrophic gastritis patients. There were 54 cases of chronic atrophic gastritis in the trial group. The positive rates of the two groups were compared and the correlation between Helicobacter pylori infection and the pathological changes of chronic gastritis was analyzed. The data were statistically analyzed by SPSS 16.0 software. Results the positive rate of the test group was 72.2%, which was significantly higher than that of the control group (37.5%). The difference between the two groups was statistically significant (P0.05). With the increase of positive rate of Helicobacter pylori infection, the degree of inflammation, intestinal metaplasia and activity of chronic gastritis increased gradually. Conclusion Helicobacter pylori infection is closely related to the pathological changes of gastric mucosa in patients with chronic gastritis and can reflect the degree of inflammation and atrophy of chronic gastritis.
【作者单位】： 温州医科大学附属第二医院病理科;温州医科大学附属第二医院麻醉科;
【基金】：浙江省科技厅基金资助项目(2016C370) 浙江省温州市科技计划基金资助项目(Y20110125)
【分类号】：R573.3
，

本文编号：2355466