胃内镜黏膜下剥离术中使用二氧化碳注气的安全性及有效性研究

发布时间：2019-02-15 16:48

【摘要】：目的该实验旨在研究二氧化碳CO_2作为胃内镜黏膜下剥离术(ESD)中注入气体的安全性及有效性。方法选取2013年1月-2014年12月于中国医科大学附属盛京医院内镜诊治中心,接受胃ESD术治疗的患者80例,40例术中注CO_2气(CO_2组),40例术中注空气(空气组),分别检测患者术前、术中及术后的动脉血CO_2分压(PaCO_2),视觉模拟评分量表(VAS)评分记录每组患者术后1、6及24 h腹痛及腹胀程度,同时记录并发症发生情况。结果两组病例整个研究过程中不同时间段PaCO_2及腹痛评分差异无统计学意义,CO_2组在ESD术后1和6 h的腹胀平均VAS分值较空气组明显降低,并发症的发生率在两组间差异无统计学意义。结论胃ESD术应用CO_2注气安全性良好。CO_2注气能够有效减轻患者术后腹胀症状,改善术后恢复质量。
[Abstract]:Objective to study the safety and efficacy of carbon dioxide CO_2 as a gas injected into gastric endoscopic submucosal dissection (ESD). Methods from January 2013 to December 2014, 80 patients were treated with gastric ESD at Shengjing Hospital affiliated to China Medical University. 40 patients received intraoperative injection of CO_2 gas (CO_2 group) and 40 cases injected air (air group). Arterial blood CO_2 partial pressure (PaCO_2) and visual analogue scale (VAS) were measured before, during and after operation to record the degree of abdominal pain and abdominal distension at 1: 6 and 24 hours after operation in each group, and the incidence of complications was recorded at the same time. Results there was no significant difference in PaCO_2 and abdominal pain score between the two groups during the whole course of the study. The mean VAS score of abdominal distention in CO_2 group was significantly lower than that in air group at 1 and 6 hours after ESD. There was no significant difference in the incidence of complications between the two groups. Conclusion it is safe to apply CO_2 gas injection in gastric ESD. CO_2 gas injection can effectively alleviate abdominal distension symptoms and improve postoperative recovery quality.
【作者单位】：中国医科大学附属盛京医院内镜诊治中心;
【分类号】：R57

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