2008-2010年绵阳地区献血人群HBV流行情况分析

发布时间：2019-03-13 21:15

【摘要】：目的统计分析绵阳地区献血人群2008年1月-2010年12月HBV的流行率、新发率,评估HBV在该地区的流行情况。方法收集2008年1月-2010年12月100 429人次献血者人口统计学资料、2轮第3代ELISA试剂初筛和确证数据。分别计算初次献血者和重复献血者的HBV流行率,利用文献报道的新发率评估模型,评估重复献血人群的新发率。结果 2008年1月-2010年12月绵阳地区初次献血和重复献血人群的HBV流行率依次为0.97%和0.04%,重复献血人群中的HBV感染新发率为0.32%。结论绵阳地区献血人群具有较高的流行率和新发率,可能引起较高的HBV输血残余风险,应考虑采用第4代ELISA初筛试剂和核酸检测(NAT)降低该地区的HBV对血液安全的影响。
[Abstract]:Objective to analyze the prevalence and new incidence of HBV among blood donors in Mianyang from January 2008 to December 2010 and to evaluate the prevalence of HBV in this area. Methods the demographic data of 100 429 blood donors from January 2008 to December 2010 were collected. The data were screened and confirmed by the third generation ELISA reagent in two rounds. The prevalence of HBV in first-time blood donors and repeated blood donors were calculated, and the new rates were evaluated by using the new rate assessment model reported in the literature. Results from January 2008 to December 2010, the prevalence of HBV in the first and repeated blood donors in Mianyang was 0.97% and 0.04%, respectively. The new rate of HBV infection was 0.32% in the repeated blood donors. Conclusion Blood donors in Mianyang area have a high prevalence rate and a new rate, which may lead to a higher residual risk of HBV transfusion. The fourth generation of ELISA screening reagent and nucleic acid detection (NAT) should be considered to reduce the effect of HBV on blood safety in this area.
【作者单位】：绵阳市红十字中心血站;中国医学科学院北京协和医学院输血研究所;
【分类号】：R512.62

【相似文献】