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节食减重与有氧运动对非酒精性脂肪肝的影响研究

发布时间:2019-03-22 10:39
【摘要】:目的比较节食减重与有氧运动分别对非酒精性脂肪肝(NAFLD)患者的改善作用。方法选取2013年5月—2015年5月在华中科技大学同济医学院附属普爱医院消化内科门诊及住院部确诊为NAFLD的患者30例,BMI 26~35 kg/m~2,平均BMI(31.8±1.6)kg/m~2。采用随机数字表法将所有患者分为A组和B组,每组15例。A组患者采用节食减重治疗,保证每天的饮食热量控制在1 500 kcal,不进行任何有氧运动。B组患者采用有氧运动治疗,每周运动3次,每次运动心率控制在最大心率(HRmax)的45%~55%,每周运动时间为150 min,同时保持既有饮食习惯,不因为运动额外增加饮食,共运动4周。比较两组干预前后ALT、空腹血糖(FPG)、血非酯化脂肪酸(FFA)、空腹胰岛素(INS)水平及胰岛素抵抗指数(HOMA-IR)、内脏脂肪组织(VAT)面积。结果两组性别、年龄比较,差异无统计学意义(P0.05);两组干预前后体质量、BMI比较,差异均无统计学意义(P0.05)。两组干预前ALT、FPG、FFA、INS水平及HOMA-IR比较,差异无统计学意义(P0.05);两组干预后ALT、FPG、INS水平及HOMA-IR比较,差异无统计学意义;B组干预后FFA水平低于A组,差异有统计学意义(P0.05)。两组干预前VAT面积比较,差异无统计学意义(P0.05);B组干预后VAT面积小于A组,差异有统计学意义(P0.05)。结论有氧运动比节食减重对NAFLD的改善作用更明显。
[Abstract]:Objective to compare the effects of diet weight loss and aerobic exercise on non-alcoholic fatty liver (NAFLD) patients. Methods from May 2013 to May 2015, 30 patients with NAFLD diagnosed in the Department of Gastroenterology and inpatient Department of Tongji Medical College affiliated to Huazhong University of Science and Technology were selected. The average BMI of BMI 26 / 35 kg/m~2, was (31.8 卤1.6) kg/m~2.. All patients were divided into two groups: group A (n = 15) and group B (n = 15). The patients in group A were treated with diet and weight loss to keep the daily diet calorie control at 1,500 kcal,. The patients in group B were treated with aerobic exercise, 3 times a week, and the heart rate of each exercise was controlled at 45% / 55% of the maximum heart rate (HRmax), and the weekly exercise time was 150 min, while maintaining the existing eating habits. A total of 4 weeks of exercise does not result in an extra diet due to exercise. Fasting blood glucose (FPG), fasting insulin (INS) (INS), insulin resistance index (HOMA-IR) and visceral adipose tissue (VAT) area were compared between the two groups before and after ALT, intervention. Results there was no significant difference in sex and age between the two groups (P0.05); there was no significant difference in body mass and BMI between the two groups before and after intervention (P0.05). There was no significant difference in the levels of ALT,FPG,FFA,INS and HOMA-IR between the two groups before intervention (P0.05), and there was no significant difference in the levels of ALT,FPG,INS and HOMA-IR between the two groups after intervention. After intervention, the level of FFA in group B was lower than that in group A, the difference was statistically significant (P0.05). There was no significant difference in the VAT area between the two groups before intervention (P0.05). The VAT area in the); B group was smaller than that in the A group after intervention, and the difference was statistically significant (P0.05). Conclusion aerobic exercise is more effective than diet in improving NAFLD.
【作者单位】: 华中科技大学同济医学院附属普爱医院消化内科;
【分类号】:R575.5

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