二氧化碳结合间苯三酚在结肠镜检查中的镇痛疗效与安全性评价

发布时间：2019-05-29 10:21

【摘要】：目的评价二氧化碳结合间苯三酚在结肠镜检查中对患者的阵痛疗效及安全性。方法入选进行结肠镜检查的患者164例,分为试验组88例和对照组76例。2组患者检查前3 d进食易消化食物,12 h和6 h前分次口服聚乙二醇电解质散清洁肠道,用二氧化碳作为肠镜检查的膨胀气体。试验组检查前10 min肌内注射间苯三酚40 mg,对照组肌内注射0.9%氯化钠2 m L。2组患者用视觉模拟评分(VAS)记录结肠镜检查过程中的疼痛评分,并观察2组患者结肠镜达到盲肠的例数及检查前、检查中和检查后血压及心率变化。结果试验组和对照组检查过程中VAS疼痛评分分别为(4.1±1.4)和(6.3±1.5),试验组显著低于对照组(P0.05)。试验组结肠镜达到盲肠者80例,达盲率为90.9%,对照组结肠镜达到盲肠者68例,达盲率为89.5%,差异无统计学意义(P0.05)。试验组与对照组结肠镜检查前、检查中及检查后收缩压、舒张压及心率差异均无统计学意义(P0.05)。结论用二氧化碳作为肠镜检查的膨胀气体,同时术前肌内注射间苯三酚可显著减轻患者结肠镜检查过中的疼痛,且无明显不良反应发生。
[Abstract]:Objective To evaluate the efficacy and safety of carbon dioxide combined with phloroglucinol during colonoscopy. Methods 164 patients with colonoscopy were divided into trial group (88 cases) and control group (76 cases). In the test group, the phloroglucinol 40 mg was intramuscularly injected for 10 min, and the control group was intramuscularly injected with 0.9% sodium chloride 2 mg/ L. The patients in the 2 group were recorded with the visual analog score (VAS) to record the pain scores during the colonoscopy, and the number of cecum and the number of cecum in the 2 groups were observed. Blood pressure and heart rate changes in and after the examination. Results The VAS pain scores were (4.1% 1.4) and (6.3% 1.5) in the test group and the control group, and the test group was significantly lower than that in the control group (P0.05). There were 80 cases of cecum in the test group, 90.9% for the control group,68 in the control group and 89.5% for the control group, and no significant difference between the control group and the control group (P0.05). The difference of systolic blood pressure, diastolic blood pressure and heart rate was not significant before and after colonoscopy in the test group and the control group (P0.05). Conclusion Carbon dioxide is used as the expansion gas of enteroscopy, while the intramuscularly intramuscularly intramuscularly intramuscularly intramuscularly injection of phloroglucinol can significantly reduce the pain of the patient's colonoscopy, and there is no obvious adverse reaction.
【作者单位】：乐清市人民医院消化内科;
【基金】：温州市医药卫生科学研究基金资助项目(2013B42)
【分类号】：R574.62

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