血液滤过联合持续区域动脉灌流对重症急性胰腺炎治疗效果的影响

发布时间：2019-08-16 17:42

【摘要】：目的:研究血液滤过联合持续区域动脉灌流对重症急性胰腺炎治疗效果的影响。方法:选择2011年9月至2013年11月我院接诊的202例重症急性胰腺炎患者进行研究,随机分为观察组和对照组。观察组100例患者,采用血液滤过配合持续区域动脉灌流治疗。对照组102例患者,采用传统的方法进行治疗。比较两组患者治疗前后各项指标。结果:治疗3~7 d后,观察组的体温低于对照组,更接近于正常体温(t=10.699 9,P0.000 1);观察组患者的心率、呼吸、血浆淀粉酶、丙氨酸氨基转移酶、尿素氮、肌酐和APACHEⅡ评分、白细胞、中性粒细胞比例均明显改善,其与对照组相比差异有统计学意义(P0.05),更接近于正常值。观察组的住院时间、腹痛缓解时间、腹胀缓解时间、肠道功能恢复时间也短于对照组,观察组的器官衰竭总例数少于对照组(P0.05)。结论:血液滤过配合持续区域动脉灌流治疗重症急性胰腺炎能有效减轻患者的过度炎症反应,能提高重症急性胰腺炎的治愈率与改善患者的预后,效果良好,值得临床推广。
[Abstract]:Objective: to study the effect of hemofiltration combined with continuous regional arterial perfusion on the treatment of severe acute pancreatitis. Methods: from September 2011 to November 2013, 202 patients with severe acute pancreatitis were randomly divided into observation group and control group. In the observation group, 100 patients were treated with hemofiltration combined with continuous regional arterial perfusion. 102 patients in the control group were treated with traditional methods. The indexes of the two groups before and after treatment were compared. Results: after 3 and 7 days of treatment, the body temperature of the observation group was lower than that of the control group, which was closer to the normal body temperature (t 鈮，

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