短节段Barrett’s食管的胃食管酸反流与餐后近端胃酸袋的相关性研究（英文）

发布时间：2021-10-16 18:06

　　目的:检测并分析短节段Barrett’s食管（BE）患者的餐后近端胃酸袋（PPGAP）的特点,并分析其与胃食管酸反流的相关性。创新点:PPGAP可能是胃食管反流病的病理因素之一,引起广泛关注,而BE患者的PPGAP特点及与反流的相关性尚无报道。方法:15名短节段BE患者和15名健康志愿者分别以牵拉法检测PPGAP的发生时间、长度、最低pH值和平均pH值。BE患者完成Gerd Q问卷调查和24 h食管pH监测。结论:短节段BE患者普遍存在PPGAP,同时PPGAP的长度和酸度与其胃食管酸反流周期数、De Meester评分和Gerd Q评分具有相关性。 

【文章来源】：Journal of Zhejiang University-Science B（Biomedicine & Biotechnology）. 2020,21(07)SCICSCD

【文章页数】：9 页

【文章目录】：
1 Introduction
2 Materials and methods
    2.1 Subjects
    2.2 Gerd Q
    2.3 Detection of PPGAPs
        2.3.1 Detection of p H changes in the distal esophagus and proximal stomach on fasting
        2.3.2 Postprandial p H changes in the distal esophagus and proximal stomach
    2.4 Esophageal 24-h p H monitoring
    2.5 Statistical analysis
3 Results
    3.1 Comparison of PPGAPs between patients with BE and healthy individuals
    3.2 PPGAP in patients with BE
    3.3 Correlations among the appearance time,length,and lowest p H of PPGAP in patients with BE
    3.4 Correlation between PPGAP and gastroesoph-ageal acid reflux in patients with BE
4 Discussion
Contributors
Compliance with ethics guidelines



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