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老年冠心病患者PCI术后不良心脏事件危险因素分析

发布时间:2018-07-03 19:08

  本文选题:冠状动脉粥样硬化性心脏病 + 经皮冠状动脉介入治疗术 ; 参考:《山东医药》2017年04期


【摘要】:目的探讨老年冠心病患者经皮冠状动脉介入治疗(PCI)术后发生不良心脏事件的危险因素。方法回顾297例老年冠心病PCI术后患者的临床资料,包括性别、年龄、BMI、文化程度、住院次数、合并高血压、合并糖尿病、合并高血脂、饮酒史、吸烟史、家族遗传史、运动情况以及随访期间不良心脏事件(心绞痛复发、心肌梗死、严重心律失常、心源性死亡)发生情况。采用SPSS20.0统计软件,以性别、年龄、BMI、文化程度、住院次数、合并高血压、合并糖尿病、合并高血脂、饮酒史、吸烟史、家族遗传史、运动情况为自变量,PCI术后不良心脏事件为因变量,先对各影响因素与PCI术后不良心脏事件发生情况的关系行单因素Logistic回归分析,对其中差异有统计学意义的因素行多因素Logistic回归分析。结果本组患者随访期间88例(29.63%)出现不良心脏事件,单因素Logistic回归分析结果表明,年龄、合并糖尿病、合并高血压、合并高血脂、饮酒史、吸烟史、家族遗传史、运动与老年冠心病患者PCI后发生不良心脏事件有关(P均0.05)。多因素Logistic回归分析结果显示,合并糖尿病OR为12.324,95%CI为5.124~32.663;吸烟OR为10.483,95%CI为4.856~20.219;合并高血压OR为8.542,95%CI为4.856~20.219;合并高血脂OR为8.158,95%CI为1.732~12.633;家族遗传史OR为7.824,95%CI为1.532~10.073;年龄≥65岁OR为6.021,95%CI为1.341~8.334。结论合并糖尿病、吸烟、合并高血压史、合并高血脂、家族遗传史、年龄超过65岁是老年冠心病患者PCI术后不良心脏事件的危险因素。
[Abstract]:Objective to investigate the risk factors of adverse cardiac events after percutaneous coronary intervention (PCI) in elderly patients with coronary heart disease. Methods the clinical data of 297 elderly patients with coronary heart disease after PCI were retrospectively reviewed, including sex, age, education, frequency of hospitalization, hypertension, diabetes mellitus, hyperlipidemia, alcohol consumption, smoking history, family genetic history. Exercise and adverse cardiac events (recurrence of angina pectoris, myocardial infarction, severe arrhythmia, cardiac death) during follow-up. SPSS 20.0 software was used to analyze sex, age BMIs, education, hospitalization times, hypertension, diabetes mellitus, hyperlipidemia, alcohol consumption, smoking history, family genetic history. Exercise condition was independent variable and adverse cardiac events after PCI were dependent variables. Univariate logistic regression analysis was performed to analyze the relationship between the influencing factors and adverse cardiac events after PCI. Multivariate logistic regression analysis was performed for the factors with statistical significance. Results 88 patients (29.63%) had adverse cardiac events during the follow-up period. Univariate logistic regression analysis showed that age, diabetes mellitus, hypertension, hyperlipidemia, alcohol consumption, smoking history, family genetic history. Exercise was associated with adverse cardiac events in elderly patients with coronary heart disease (P 0.05). The results of multivariate logistic regression analysis showed that the OR of diabetes mellitus was 5.124 卤32.663, OR of smoking was 10.483,95CI was 4.856 卤20.219, OR of hypertension was 8.542.95CI was 4.85620.219, OR of hyperlipidemia was 8.15895CI was 1.73212.633, the genetic history of family was 7.824995 CI was 1.53210.073; the OR of age 鈮,

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