普米克令舒联合金喉健雾化吸入治疗声带息肉术后疗效观察

发布时间：2018-09-18 06:30

【摘要】：目的:观察普米克令舒、金喉健联合雾化吸入治疗声带息肉术后疗效。方法:将临床确诊为声带息肉90例患者随机分为两组:两组均为在手术后给予抗感染全身用药综合治疗基础上,普米克令舒组50例应用普米克令舒、金喉健联合雾化吸入(普米克令舒1mg/次+金喉健1mg/次,2次/d,共7d);地塞米松组40例给予地塞米松及庆大霉素雾化吸入(地塞米松5mg/次+庆大霉素8万U/次,2次/d,共7d)。观察用药后患者声嘶减轻、消退时间及声带充血水肿改善情况。结果:与地塞米松组比较,普米克令舒组症状、体征改善优于对照组,病程缩短,疗效明显好于对照组(P=0.030)。两组患者均未发现副作用及不良反应。结论:普米克令舒、金喉健联合雾化吸入治疗声带息肉术后,可以明显改善症状及缩短病程,提高治愈率,方法简单安全,避免全身使用激素的不良反应,值得临床推广。
[Abstract]:Objective: to observe the effect of combined inhalation of Pulmicort and Jinluojian in the treatment of vocal cord polyps. Methods: 90 patients with vocal cord polyps were randomly divided into two groups: the two groups were treated with systemic anti-infective drugs after operation, and 50 patients in the Pulmicort Resu group were treated with Pulmicort Resu. The patients in the dexamethasone group were treated with dexamethasone and gentamicin aerosol inhalation (dexamethasone 5mg/ 80000 U / time 2 / d for 7 days) and dexamethasone group (40 cases received dexamethasone and gentamicin inhalation for 7 days). To observe the relief of hoarseness, the time of regression and the improvement of hyperemia and edema of vocal cord after treatment. Results: compared with the dexamethasone group, the improvement of symptoms and signs in the Pulmicort group was better than that in the control group, the course of disease was shorter and the curative effect was better than that in the control group (P0. 030). No side effects or adverse reactions were found in both groups. Conclusion: after the treatment of vocal cord polyps by combined inhalation of Pulmicort and Jinluojian, it can obviously improve symptoms and shorten the course of disease, increase the cure rate. The method is simple and safe, and can avoid the adverse reaction of using hormones all over the body. It is worth popularizing in clinic.
【作者单位】：首都医科大学附属北京安贞医院耳鼻咽喉头颈外科;首都医科大学附属北京儿童医院北京市儿科研究所儿童耳鼻喉头颈外科疾病北京市重点实验室;
【基金】：国家国际科技合作专项项目(No.2012DFG31620)~~
【分类号】：R767.91

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