2012～2014年武汉地区34家医院保肝药应用分析

发布时间：2018-02-15 09:13

本文关键词： 保肝药药物利用限定日剂量武汉地区　出处：《药物流行病学杂志》2016年02期 　论文类型：期刊论文

【摘要】：目的:对武汉地区2012~2014年保肝药物临床应用情况进行分析,为临床合理用药和科学管理提供参考。方法:采用世界卫生组织推荐的限定日剂量为指标的分析方法,对武汉地区2012~2014年34家样本医院保肝药总销售金额、用药频度(DDDs)、限定日费用(DDC)、排序比等进行回顾性统计分析。结果:武汉地区2012~2014年保肝药总体销售金额和用药频度逐年升高,排序前10位的品种变化不大。每年均以异甘草酸镁销售金额最高,其次是鸟氨酸-门冬氨酸,核糖核酸,甘草甜素、半胱氨酸疏基丙氨酸复方制剂和多烯磷脂酰胆碱。2012~2013年用药频度居于前2位的是甘草甜素、半胱氨酸疏基丙氨酸复方制剂和水飞蓟素,2014年是促肝细胞生长素和苦参素。3年来,金额排名前30位的药品中,每年均有7个品种排序比小于0.5。结论:武汉地区保肝药的市场前景广阔,临床应用基本合理,但仍存在个别品种应用不合理的情况。
[Abstract]:Objective: to analyze the clinical application of hepatoprotective drugs in Wuhan from 2012 to 2014 so as to provide a reference for rational drug use and scientific management. Methods: the limited daily dose recommended by the World Health Organization (WHO) was used as an index. A retrospective statistical analysis was made on the total sales amount of liver protection drugs, the frequency of drug use, the limited daily cost and the ranking ratio of liver protection drugs in 34 sample hospitals in Wuhan from 2012 to 2014. Results: the total sales amount and the frequency of liver protection drugs in Wuhan area increased year by year. The order of the top 10 varieties changed little. Magnesium isoglycyrrhizinate sold the most money every year, followed by ornithine aspartate, ribonucleic acid, glycyrrhizin, In 2013, glycyrrhizin, cysteine, cysteine and silymarin were two of the most frequently used formulations and polyenylphosphatidylcholine. In the past 3 years, they were hepatocyte growth-promoting hormone and matrine. Among the top 30 drugs in total amount of money, the ranking ratio of 7 varieties per year is less than 0.5. Conclusion: the market prospect of liver protection drugs in Wuhan area is broad and the clinical application is basically reasonable, but there are still some unreasonable cases in the application of some kinds of drugs.
【作者单位】：华中科技大学同济医学院附属同济医院药学部;
【分类号】：R969.3

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