2011～2015年中国银川地区男男性行为人群HIV-1感染率和新发感染率趋势研究

发布时间：2018-01-13 22:33

本文关键词：2011～2015年中国银川地区男男性行为人群HIV-1感染率和新发感染率趋势研究　出处：《病毒学报》2017年03期 　论文类型：期刊论文

【摘要】：调查2011~2015年中国宁夏银川地区男男性行为人群MSM(Men who have sex with men,MSM)HIV-1感染率和新发感染率的变化趋势,为高危特殊人群干预防治提供科学策略。2011~2015年在银川地区进行MSM哨点监测,调查MSM人群社会人口学信息、性行为情况、艾滋病预防服务覆盖和近1年HIV检测情况等,采用趋势χ2检验进行趋势分析;MSM确证结果为HIV-1阳性样本进行BED检测,计算新发感染率并进行χ2检验。2011~2015年在银川地区每年均调查MSM人群400例,HIV感染率分别为3.8%(95%Cl:2.3%~5.6%)、7.3%(95%CI:5.1%~12.3%)、5.5%(95%Cl:3.5%~8.0%)、6.0%(95%Cl:4.6%~8.6%)和8.3%(95%C1:6.4%~12.6%),未见有上升趋势(P=0.335);梅毒感染率分别为7.0%(95%CI:5.8%~10.2%)、6.3%(95%CI:4.1%~10.0%)、5.5%(95%CI:4.3%~7.9%)、6.8%(95%CI:5.3%~12.9%)和5.0%(95%Cl:4.0%~7.7%),未见有上升趋势(P=0.315);最近6个月与同性发生肛交行为的MSM中,安全套的使用率从2011年的40.8%下降至2015年的11.5%;最近6个月与同性发生商业性行为的比例从2011年的16.0%至2015年的15.0%,而在同性商业性行为中安全套的使用率从85.9%上升至90.0%,最近6个月与异性发生性行为的MSM中,从2011年41.5%至2015年24.3%,呈逐年减少趋势,与异性发现性行为安全套的使用率从38.0%下降至7.2%。2011~2015年新发感染率分别为2.88%(95%CI:0.36%~5.40%)、5.70%(95%CI:2.17%~9.23%)、5.19%(95%CI:1.97%~8.41%)、5.73%(95%CI:2.35%~9.12%)、5.28%(95%CI:2.01%~8.55%),卡方检验显示,P0.05(χ2=2.478,P=0.629),差异无统计学意义。银川地区MSM人群HIV感染率和新发感染率保持稳定态势;MSM人群存在严重的认知行为分离现象,MSMW人群是艾滋病防治中的重点难点人群。
[Abstract]:MSM(Men who have sex with men (MSM(Men who have sex with men) was investigated in Yinchuan, Ningxia, China from 2011 to 2015. The change trend of MSM)HIV-1 infection rate and new infection rate, providing scientific strategy for intervention and prevention of high risk special population. From 2011 to 2015, MSM sentinel surveillance was carried out in Yinchuan area. To investigate the social demographic information, sexual behavior, HIV / AIDS prevention service coverage and HIV detection in the past 1 year in MSM population, the trend analysis was carried out by using trend 蠂 2 test. MSM confirmed that the positive samples of HIV-1 were detected by BED, and the new infection rate was calculated. From 2001 to 2015, 400 cases of MSM were investigated in Yinchuan area. The infection rate of HIV was 3.895 / Cl: 2.3and 5.6and 7.3and 9.95%: 5.1and 12.31. respectively. 5. 5: 95 I have 8. 0 and 8. 0. I have about 6. 0 and 95. I'm about 4. 6 and 8. 6) and I'm about 8. 3 (95: 6. 4 percent and 12. 6 percent). No upward trend was found. The syphilis infection rate was 7. 0% and 95% CI: 5. 8% and 10. 2%, 10. 3% and 10. 0% respectively. 5. 5 and 95% I have 7. 9%, and 6. 8 and 95. I have 5. 3 and 12. 9.) and 5. 0 and 95. I have 1: 4. 0 and 7. 7). There was no upward trend of 0.315%; In MSM, which had anal sex with the same sex in the last 6 months, the condom use rate decreased from 40.8% in 2011 to 11.5 in 2015; The proportion of commercial sex with the same sex in the last six months ranged from 16.0% in 2011 to 15.0% in 2015. Condom use in same-sex commercial sex rose from 85.9% to 90. 0 in MSM, which had sex with the opposite sex in the last 6 months. From 2011 to 2015, 24.3B showed a decreasing trend year by year. The prevalence rate of condom discovery with heterosexual sex decreased from 38.0% to 7.2. 2011-#date0# and was 2.88% (P < 0.05). 95 CI: 0.36 and 5.40. 5.70: 2.17 I have 9.23, and I have 5.19. I have 1. 97 and 8. 41. 5.73 and 95% I have 9. 12%, 5. 2828 and 95% I have 8. 55 points, chi-square test shows. P0.05 (蠂 ~ 2 = 2.478), there was no significant difference in HIV infection rate and new infection rate among MSM population in Yinchuan area. There is a serious cognitive behavior segregation phenomenon in MSM population. MSMW population is the key and difficult population in AIDS prevention and treatment.
【作者单位】：宁夏疾病预防控制中心;宁夏医科大学;
【基金】：宁夏自然科学基金(项目号:NZ13217),题目:宁夏静脉吸毒人群HCV发病率新方法的建立及应用宁夏科技攻关计划项目国际合作专项(项目号:2013ZYH193),题目:宁夏丙型肝炎分子流行病学调查及干预模式的建立~~
【分类号】：R181.3;R512.91
【正文快照】： 艾滋病,获得性免疫缺陷综合征(Acquired im-mune deficiency syndrome,AIDS),是由于人类感染了人类免疫缺陷病毒(Human immunodificiencyvirus,HIV)而造成人类免疫系统缺陷的疾病。男男性行为人群MSM(Men who have sex with men,MSM)由于其多性伴和无保护肛交等特点成为HIV感

【相似文献】